Chen Shuo, Chen Feng, Xu Xiao
Department of Radiology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Department of Radiology, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, Zhejiang, China.
Front Oncol. 2023 Oct 18;13:1185129. doi: 10.3389/fonc.2023.1185129. eCollection 2023.
Endodermal sinus tumors are rare, especially extragonadal endodermal sinus tumors, which often occur in the midline of the brain, neck, chest, and abdomen.
We present the case of a 37-year-old woman with a mass on the right edge of the liver. Color Doppler ultrasound, computed tomography, and magnetic resonance imaging examinations were performed before the operation. Given these results and the elevation of alpha-fetoprotein, the diagnosis of hepatocellular carcinoma was made. Postoperative pathological examination indicated an endodermal sinus tumor on the abdominal wall near the right liver. The causes of misdiagnosis were analyzed, and the related literature was reviewed.
Primary endodermal sinus tumors on the abdominal wall near the right liver are easily misdiagnosed as hepatocellular carcinoma due to liver compression and elevated alpha-fetoprotein. The key point of differentiation is the wide basal connection between the tumor and the abdominal wall near the liver. In addition, the enhancement mode of endodermal sinus tumors is different from the enhancement pattern of hepatocellular carcinoma.
Extragonadal endodermal sinus tumors often occur in the midline of the body. Here, we present a case of a primary endodermal sinus tumor on the abdominal wall near the right liver for the first time.
内胚窦瘤罕见,尤其是性腺外内胚窦瘤,常发生于脑、颈部、胸部和腹部的中线部位。
我们报告一例37岁女性,其肝脏右缘有一肿块。术前进行了彩色多普勒超声、计算机断层扫描和磁共振成像检查。根据这些结果及甲胎蛋白升高情况,诊断为肝细胞癌。术后病理检查显示右肝附近腹壁有内胚窦瘤。分析了误诊原因并复习了相关文献。
右肝附近腹壁的原发性内胚窦瘤由于肝脏受压和甲胎蛋白升高,易被误诊为肝细胞癌。鉴别要点是肿瘤与肝脏附近腹壁之间有较宽基底连接。此外,内胚窦瘤的强化方式与肝细胞癌不同。
性腺外内胚窦瘤常发生于身体中线部位。在此,我们首次报告一例右肝附近腹壁原发性内胚窦瘤病例。