Medina Gaviria V, González Villarreal L, Molina Ramírez I, Jaramillo Barberi L, Sebá Becerra J
Servicio de Cirugía Pediátrica. Universidad Nacional de Colombia-Fundación Hospital Pediátrico de la Misericordia (HOMI). Colombia.
Cir Pediatr. 2019 Apr 22;32(2):104-108.
Endodermal sinus tumor is a malignant germ cell tumor that generally involves the gonads. Extra-gonadal localization out of midline organs is rare. We report a case of endodermal sinus tumor in the thoracoabdominal wall.
We discuss the case of an infant presenting an abdominal mass detected after a fall from his own height. Studies revealed anemia with abundant intraabdominal fluid and elevated alpha-fetoprotein. During surgery, a left thoracoabdominal wall-dependent tumor was identified, with involvement of the diaphragm and the costal cartilage. Complete resection was performed. Pathology report informed of an endodermal sinus tumor.
Abdominal wall location of endodermal sinus tumor is rare. Pathophysiology has not been completely outlined, however, it is presumed to be a consequence of aberrant migration patterns of the primordial cells. Pre-surgical diagnosis remains a challenge due to the low incidence.
内胚窦瘤是一种恶性生殖细胞肿瘤，通常累及性腺。中线器官以外的性腺外定位很少见。我们报告一例胸腹壁内胚窦瘤病例。
我们讨论了一名婴儿的病例，该婴儿在从自身高度跌落之后被发现腹部有肿块。检查显示有贫血、大量腹腔积液和甲胎蛋白升高。手术过程中，发现一个位于左胸腹壁的肿瘤，累及膈肌和肋软骨。进行了完整切除。病理报告显示为内胚窦瘤。
内胚窦瘤位于腹壁的情况很罕见。虽然病理生理学尚未完全阐明，但推测是原始细胞异常迁移模式的结果。由于发病率低，术前诊断仍然是一项挑战。
