Keefe M, Wakeel R A, McBride D I
Department of Dermatology, Stobhill General Hospital, Glasgow, Scotland.
Arch Dermatol. 1988 Jul;124(7):1077-9.
An 82-year-old man presented with rapid enlargement of a long-standing rhinophyma. Following an uncomplicated excision of rhinophyma, histologic examination showed that the enlargement was entirely due to basal cell carcinoma. Radiotherapy was administered, and the nose has now healed satisfactorily. There are few reports of an association between rhinophyma and basal cell carcinoma; but it is claimed that it occurs more frequently than is expected by chance. The evidence for this is reviewed. Previous reports were anecdotal or contained biases that prevent generalization of the results and, in addition, a statistical analysis was incorrect. There is insufficient evidence to claim an association between basal cell carcinoma and rhinophyma.
一名82岁男性因长期存在的鼻赘迅速增大前来就诊。在顺利切除鼻赘后,组织学检查显示其增大完全是由基底细胞癌所致。患者接受了放射治疗,目前鼻部愈合良好。关于鼻赘与基底细胞癌之间关联的报道较少;但据称这种情况的发生频率高于偶然预期。本文对这方面的证据进行了综述。既往报道多为轶事性或存在偏差,无法对结果进行推广,此外,统计分析也不正确。尚无足够证据表明基底细胞癌与鼻赘之间存在关联。