美国 种复合体和 分离株对米诺环素的敏感性趋势。2014-2021 年。
Trends in the susceptibility of U.S. species complex and isolates to minocycline, 2014-2021.
机构信息
University of Iowa , Iowa City, Iowa, USA.
JMI Laboratories , North Liberty, Iowa, USA.
出版信息
Microbiol Spectr. 2023 Dec 12;11(6):e0198123. doi: 10.1128/spectrum.01981-23. Epub 2023 Nov 3.
Abstract
species complex and are opportunistic, non-fermentative Gram-negative organisms that can cause serious hospital-acquired infections in immunocompromised patients. These pathogens are inherently resistant to several common drug classes and often acquire other resistance mechanisms, making them difficult to treat. In this study, we analyzed the trends of susceptibility of over 2,500 U.S. bacterial isolates collected from hospitalized patients over an 8-year period to minocycline, which is used to treat infections caused by these pathogens. These data suggest that minocycline is a useful treatment option for infections caused by species complex or .
摘要
种复合体和 是机会性、非发酵革兰氏阴性生物体，可在免疫功能低下的患者中引起严重的医院获得性感染。这些病原体对几种常见的药物类别具有固有抗性，并且经常获得其他抗性机制，因此难以治疗。在这项研究中，我们分析了 8 年来从住院患者中收集的超过 2500 个美国细菌分离株对米诺环素的敏感性趋势，米诺环素用于治疗这些病原体引起的感染。这些数据表明，米诺环素是治疗 种复合体或 引起的感染的一种有用的治疗选择。
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