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1999-2020 年美国成年人骨折患病率趋势:一项基于人群的研究。

Trends in prevalence of fractures among adults in the United States, 1999-2020: a population-based study.

机构信息

The Second Hospital of Shandong University.

Department of Orthopedic Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea.

出版信息

Int J Surg. 2024 Feb 1;110(2):721-732. doi: 10.1097/JS9.0000000000000883.

DOI:10.1097/JS9.0000000000000883
PMID:37921645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10871608/
Abstract

BACKGROUND

Population data that examines recent national trends in the prevalence of fractures are lacking in the United States (US).

MATERIALS AND METHODS

Analyses were based on 1999-2020 data from the National Health and Nutrition Examination Survey (NHANES). Primary outcomes included the prevalence of hip, wrist, and vertebral fractures among adults aged greater than or equal to 50 years. Changes in the prevalence over time were determined by joinpoint regression analysis. The authors also described the variation by fracture subtypes, sociodemographic characteristics, and their combination.

RESULTS

For adults aged greater than or equal to 50 years in NHANES 2017-March 2020, the authors estimated that there was 2.6 million Americans with hip fractures, 14.6 million Americans with wrist fractures, and 5.2 million Americans with vertebral fractures. The prevalence of wrist fractures significantly increased from 8.7% (7.4-9.9%) in 1999-2000 to 12.8% (11.6-14.1%) in 2017-March 2020 among adults aged greater than or equal to 50 years ( P for trend=0.04); significant increases were also observed in fractures that occurred at age less than 50 years, non-Hispanic White, high family income groups, and several combination subgroups (e.g. fractures occurred at age <50 years among women). The prevalence of vertebral fractures increased from 2.2% (1.7-2.8%) in 1999-2000 to 4.6% (3.7-5.5%) in 2017-March 2020 among adults aged greater than or equal to 50 years ( P for trend=0.02); significant increases were also observed in 50-64 years, women, non-Hispanic White, high family income groups and several combination subgroups (e.g. fractures that occurred at age <50 years among women). The authors did not observe significant trend changes in the prevalence of hip fractures among adults aged greater than or equal to 50 years between 1999 and 2020.

CONCLUSION

The estimated prevalence of wrist and vertebral fractures significantly increased among US adults aged greater than or equal to 50 years from 1999 to 2020, although hip fractures did not significantly change.

摘要

背景

美国缺乏关于骨折流行率的近期全国趋势的人口数据。

材料和方法

分析基于 1999-2020 年国家健康和营养检查调查(NHANES)的数据。主要结果包括 50 岁及以上成年人髋部、腕部和椎体骨折的流行率。通过联合回归分析确定随时间变化的流行率变化。作者还描述了骨折亚型、社会人口特征及其组合的变化。

结果

在 NHANES 2017 年 3 月至 2020 年期间,50 岁及以上的成年人中,作者估计有 260 万美国人髋部骨折,1460 万美国人腕部骨折,520 万美国人椎体骨折。50 岁及以上成年人的腕部骨折流行率从 1999-2000 年的 8.7%(7.4-9.9%)显著增加到 2017 年 3 月至 2020 年的 12.8%(11.6-14.1%)(趋势 P=0.04);在年龄小于 50 岁、非西班牙裔白人、高家庭收入群体和几个组合亚组(例如,50 岁以下女性发生骨折)中也观察到显著增加。50 岁及以上成年人的椎体骨折流行率从 1999-2000 年的 2.2%(1.7-2.8%)增加到 2017 年 3 月至 2020 年的 4.6%(3.7-5.5%)(趋势 P=0.02);在 50-64 岁、女性、非西班牙裔白人、高家庭收入群体和几个组合亚组(例如,50 岁以下女性发生骨折)中也观察到显著增加。作者没有观察到 1999 年至 2020 年间 50 岁及以上成年人髋部骨折流行率的显著趋势变化。

结论

1999 年至 2020 年,美国 50 岁及以上成年人的腕部和椎体骨折的估计流行率显著增加,而髋部骨折没有显著变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/8f67f29376c6/js9-110-0721-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/11bba6d78aaa/js9-110-0721-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/48c2d571e59b/js9-110-0721-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/1ffa0a66bf3c/js9-110-0721-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/3ebb69c0fbb2/js9-110-0721-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/8f67f29376c6/js9-110-0721-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/11bba6d78aaa/js9-110-0721-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/48c2d571e59b/js9-110-0721-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/1ffa0a66bf3c/js9-110-0721-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/3ebb69c0fbb2/js9-110-0721-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/043e/10871608/8f67f29376c6/js9-110-0721-g005.jpg

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