Suppr超能文献

探索健康保险计划对生物类似药采用率的影响。

Exploring the Influence of Health Insurance Plans on Biosimilar Adoption Rates.

作者信息

Costin Jeremy, Mouslim Morgane C, Socal Mariana P, Trujillo Antonio

机构信息

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

The Hilltop Institute, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA.

出版信息

Pharmacoecon Open. 2024 Jan;8(1):115-118. doi: 10.1007/s41669-023-00447-6. Epub 2023 Nov 3.

Abstract

BACKGROUND

We conducted a study to investigate the role of health insurance plans on biosimilar adoption among commercially insured patients in the USA. Flexible and rigid health plans may exhibit differing biosimilar coverage due to variations in cost considerations, formulary design, and provider networks.

OBJECTIVE

To identify the characteristics of switchers and biosimilar initiators for six biologic-biosimilar pairs.

METHODS

Using claims data from 2015 to 2019, we implement sequential regression models to assess the role of health plans on biosimilars adoption.

FINDINGS

We found that low-flexibility plans, such as Health Maintenance Organization (HMOs) and Exclusive Provider Organization (EPOs), are more likely to have patients who are switchers and/or biosimilar initiators.

CONCLUSION

Our findings highlight the importance of health insurance plan design in promoting biosimilar uptake.

摘要

背景

我们开展了一项研究,以调查医疗保险计划在美国商业保险患者中对生物类似药采用情况的作用。灵活和严格的健康计划可能因成本考量、处方集设计和供应商网络的差异而呈现出不同的生物类似药覆盖范围。

目的

确定六对生物药-生物类似药组合的换药者和生物类似药起始使用者的特征。

方法

利用2015年至2019年的理赔数据,我们实施了序贯回归模型,以评估健康计划对生物类似药采用情况的作用。

结果

我们发现,低灵活性计划,如健康维护组织(HMO)和独家供应商组织(EPO),更有可能拥有换药者和/或生物类似药起始使用者。

结论

我们的研究结果凸显了医疗保险计划设计在促进生物类似药使用方面的重要性。

相似文献

1
Exploring the Influence of Health Insurance Plans on Biosimilar Adoption Rates.
Pharmacoecon Open. 2024 Jan;8(1):115-118. doi: 10.1007/s41669-023-00447-6. Epub 2023 Nov 3.
2
Biosimilar formulary placement in Medicare Part D prescription drug plans: A case study of infliximab.
Am J Health Syst Pharm. 2021 Jan 22;78(3):216-221. doi: 10.1093/ajhp/zxaa376.
3
Factors Associated with Biosimilar Exclusions and Step Therapy Restrictions Among US Commercial Health Plans.
BioDrugs. 2023 Jul;37(4):531-540. doi: 10.1007/s40259-023-00593-7. Epub 2023 Apr 1.
4
Filgrastim and infliximab biosimilar uptake in Medicare Advantage compared with Traditional Medicare, 2016-2019.
J Manag Care Spec Pharm. 2024 Jan;30(1):15-21. doi: 10.18553/jmcp.2024.30.1.15.
5
Patient Out-of-Pocket Costs for Biologic Drugs After Biosimilar Competition.
JAMA Health Forum. 2024 Mar 1;5(3):e235429. doi: 10.1001/jamahealthforum.2023.5429.
6
Biosimilar strategic implementation at a large health system.
Am J Health Syst Pharm. 2022 Feb 8;79(4):268-275. doi: 10.1093/ajhp/zxab410.
8
Biosimilars: Opportunities to Promote Optimization Through Payer and Provider Collaboration.
J Manag Care Spec Pharm. 2016 Sep;22(9 Suppl):S3-9. doi: 10.18553/jmcp.2016.22.9-a.s3.
9
Overcoming barriers to biosimilar adoption: real-world perspectives from a national payer and provider initiative.
J Manag Care Spec Pharm. 2021 Aug;27(8):1129-1135. doi: 10.18553/jmcp.2021.27.8.1129.
10
Real-world evidence of a successful biosimilar adoption program.
Future Oncol. 2022 May;18(16):1997-2006. doi: 10.2217/fon-2021-1584. Epub 2022 Mar 17.

引用本文的文献

1
Beyond cost: a value-based framework for biosimilar procurement in emerging markets - the Thai experience.
J Pharm Policy Pract. 2025 Jul 10;18(1):2526827. doi: 10.1080/20523211.2025.2526827. eCollection 2025.
3
Mitigating the Nocebo Effect in Biosimilar Use and Switching: A Systematic Review.
Pharmaceut Med. 2024 Nov;38(6):429-455. doi: 10.1007/s40290-024-00541-y. Epub 2024 Nov 29.

本文引用的文献

1
The Automatic Substitution of Biosimilars: Definitions of Interchangeability are not Interchangeable.
Adv Ther. 2021 May;38(5):2077-2093. doi: 10.1007/s12325-021-01688-9. Epub 2021 Mar 21.
3
Why Are Biosimilars Not Living up to Their Promise in the US?
AMA J Ethics. 2019 Aug 1;21(8):E668-678. doi: 10.1001/amajethics.2019.668.
4
Patient attitudes about non-medical switching to biosimilars: results from an online patient survey in the United States.
Curr Med Res Opin. 2019 Apr;35(4):603-609. doi: 10.1080/03007995.2018.1560221. Epub 2019 Jan 8.
5
Determinants of HMO formulary adoption decisions.
Health Serv Res. 2003 Feb;38(1 Pt 1):169-90. doi: 10.1111/1475-6773.t01-1-00111.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验