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预后营养指数和改良衰弱指数是老年骨质疏松性椎体压缩骨折患者再压缩的独立危险因素。

Prognostic nutritional index and modified frailty index, independent risk factors for recompression in elderly patients with osteoporotic vertebral compression fractures.

机构信息

Department of Orthopedics, The Afliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, No. 366 Taihu Road, Taizhou City, 225300, Jiangsu Province, China.

Chengdong Street Community Medical Service Center, Taizhou, China.

出版信息

Eur Spine J. 2024 Apr;33(4):1518-1523. doi: 10.1007/s00586-023-08016-5. Epub 2023 Nov 3.

Abstract

BACKGROUND

To identify some clinical and laboratory independent risk factors for postoperative recompression among elderly osteoporotic vertebral compression fractures (OVCF) patients.

METHODS

A retrospective analysis was conducted on 287 elderly OVCF patients after percutaneous vertebroplasty (PVP). Relevant risk factors for recompression were screened and further analyzed through multivariate logistic regression.

RESULTS

Within postoperative 1 year, recompression had occurred in 72 patients, with an incidence of 25.1% (72/287). Multivariate logistic analysis indicated that mean spinal BMD <  - 2.85 (OR: 4.55, 95%CI 2.22-9.31, P < 0.001), ODI ≥ 68.05% (OR: 6.78, 95%CI 3.16-14.55, P < 0.001), PNI score < 43.1 (OR: 2.81, 95%CI 1.34-5.82, P = 0.005), and mFI score ≥ 0.225 (OR: 8.30, 95%CI 3.14-21.95, P < 0.001) were four distinct risk factors that independently contributed to postoperative recompression.

CONCLUSIONS

Spinal BMD, ODI, PNI and mFI independently predict recompression in OVCF patients after PVP treatment.

摘要

背景

确定老年骨质疏松性椎体压缩性骨折(OVCF)患者经皮椎体成形术后再压缩的一些临床和实验室独立危险因素。

方法

对 287 例老年 OVCF 患者行经皮椎体成形术(PVP)后进行回顾性分析。筛选出与再压缩相关的危险因素,并通过多变量逻辑回归进一步分析。

结果

术后 1 年内,72 例患者发生再压缩,发生率为 25.1%(72/287)。多变量逻辑分析表明,平均脊柱 BMD<-2.85(OR:4.55,95%CI 2.22-9.31,P<0.001),ODI≥68.05%(OR:6.78,95%CI 3.16-14.55,P<0.001),PNI 评分<43.1(OR:2.81,95%CI 1.34-5.82,P=0.005),mFI 评分≥0.225(OR:8.30,95%CI 3.14-21.95,P<0.001)是与术后再压缩独立相关的四个显著危险因素。

结论

脊柱 BMD、ODI、PNI 和 mFI 独立预测 PVP 治疗后 OVCF 患者的再压缩。

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