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急慢性主动脉夹层:不稳定“三腔”主动脉的处理和结局。

Acute-on-Chronic Aortic Dissection: Management and Outcomes of the Unstable "Triple-Lumen" Aorta.

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia.

Rollins School of Public Health, Emory University, Atlanta, Georgia.

出版信息

Ann Thorac Surg. 2024 May;117(5):923-930. doi: 10.1016/j.athoracsur.2023.10.029. Epub 2023 Nov 2.

DOI:10.1016/j.athoracsur.2023.10.029
PMID:37923239
Abstract

BACKGROUND

The impact of acute aortic dissection of the chronically dissected distal aorta is unknown. This study sought to describe the incidence and characteristics of the triple-lumen aortic dissection and its impact on survival.

METHODS

From 2010 to 2021, a query of a single-institution aortic database identified 1149 patients with chronic distal aortic dissection. Thirty-three (2.9%) patients with at least 3 distinct lumens and 2 separate "primary" intimal tears were identified by analysis of contrast-enhanced cross-sectional imaging. Triple-lumen patients were exactly matched with a cohort of double-lumen patients on a 1:1 ratio using 5 preoperative variables, and outcomes between the groups were assessed.

RESULTS

The median age at time of initial dissection in patients with a triple-lumen dissection was 46 years. Initial dissection was a type A in 33% and a type B in 67% of patients. The median time from initial dissection to triple-lumen diagnosis was 4.2 years. On diagnosis of the triple-lumen aorta, 85% of patients required urgent aortic repair for rapid growth (36%), aortic diameter ≥55 mm (30%), malperfusion (6%), intractable pain (6%), and rupture/type A (6%). Thirty-day mortality after triple lumen dissection was 12%.

CONCLUSIONS

Acute-on-chronic distal dissection resulting in a triple-lumen aorta should be classified as a "complicated" type B dissection as these patients typically have large aneurysms and a high incidence of rapid false lumen expansion requiring urgent surgical repair.

摘要

背景

慢性夹层远端主动脉急性夹层的影响尚不清楚。本研究旨在描述三腔主动脉夹层的发生率和特征及其对生存率的影响。

方法

2010 年至 2021 年,通过对单一机构主动脉数据库的查询,确定了 1149 例慢性远端主动脉夹层患者。通过对增强横断面成像的分析,发现了 33 例至少有 3 个不同腔和 2 个独立“原发性”内膜撕裂的三腔患者。通过对 5 个术前变量进行 1:1 配对,对三腔患者与双腔患者进行了精确匹配,并评估了两组之间的结果。

结果

三腔夹层患者初次夹层时的中位年龄为 46 岁。初次夹层为 A 型者占 33%,B 型者占 67%。从初次夹层到三腔诊断的中位时间为 4.2 年。在诊断为三腔主动脉时,85%的患者因快速生长(36%)、主动脉直径≥55mm(30%)、灌注不良(6%)、难治性疼痛(6%)和破裂/型 A(6%)需要紧急主动脉修复。三腔夹层后 30 天死亡率为 12%。

结论

慢性夹层远端急性夹层导致的三腔主动脉应被归类为“复杂”型 B 夹层,因为这些患者通常有大的动脉瘤,并且快速假腔扩张的发生率很高,需要紧急手术修复。

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