Conway Janet D, Annasamudram Abhijith, Abalkhail Talal, Tom Jalen H, Farley Robert P, Gesheff Martin, Elhessy Ahmed H
Orthopedics, International Center for Limb Lengthening, Rubin Institute of Advanced Orthopedics, Baltimore, USA.
Orthopaedics, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU.
Cureus. 2023 Oct 3;15(10):e46397. doi: 10.7759/cureus.46397. eCollection 2023 Oct.
As the occurrence of total knee arthroplasties (TKAs) is forecasted to continue rising, so too will the frequency of prosthetic joint infections (PJIs) and revision TKAs. Multiple revisions can result in an unreconstructible knee. In such instances, the knee may be salvaged through arthrodesis. We evaluated whether height, BMI, and age impacted patient-reported outcome measures (PROMs) in patients who underwent knee arthrodesis after revision TKA due to PJI.
We conducted a retrospective review of patients undergoing arthrodesis for an infected TKA at a dedicated orthopedic infection service from 2014 to 2022. Patient demographics and PROMs from 36-Item Short Form Survey (SF-36) and Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaires were collected. Correlation analysis was performed to determine if any association between height, BMI, and age was present with the various PROMs and sub-scores.
Forty-four patients (19 males, 25 females) were included, with a mean follow-up of 48 months. Increases in height (>166 cm), BMI (>30), and age (>62 years) had a statistically significant negative impact on three SF-36 components: health changes (P = 0.016), physical functioning ability (P = 0.0096), and general health components (P = 0.0075).
Our results suggest that a knee arthrodesis is an acceptable option in patients with a persistent knee PJI with good functional PROMs and ambulatory status. Patients with shorter height, lower BMI, and younger age showed overall better outcomes. Knee arthrodesis can be an alternative option for amputation in patients with an infected TKA and provide good functional outcomes in selected patients.
由于全膝关节置换术(TKA)的发生率预计将持续上升,假体关节感染(PJI)和翻修TKA的频率也会随之增加。多次翻修可能导致膝关节无法重建。在这种情况下,可通过关节融合术挽救膝关节。我们评估了身高、体重指数(BMI)和年龄是否会影响因PJI接受TKA翻修术后行膝关节融合术患者的患者报告结局指标(PROMs)。
我们对2014年至2022年在一家专门的骨科感染科因感染性TKA接受关节融合术的患者进行了回顾性研究。收集了患者的人口统计学数据以及来自36项简明健康调查问卷(SF-36)和膝关节损伤与骨关节炎结局评分(KOOS)问卷的PROMs。进行相关性分析以确定身高、BMI和年龄与各种PROMs及子评分之间是否存在关联。
纳入44例患者(19例男性,25例女性),平均随访48个月。身高增加(>166 cm)、BMI增加(>30)和年龄增加(>62岁)对SF-36的三个组成部分有统计学显著的负面影响:健康变化(P = 0.016)、身体功能能力(P = 0.0096)和总体健康组成部分(P = 0.0075)。
我们的结果表明,对于持续存在膝关节PJI且PROMs功能良好和活动状态良好的患者,膝关节融合术是一种可接受的选择。身高较矮、BMI较低和年龄较小的患者总体结局较好。膝关节融合术可作为感染性TKA患者截肢的替代选择,并在选定患者中提供良好的功能结局。