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髓内顺行杆膝关节融合术治疗慢性感染全膝关节置换术后感染

Knee Arthrodesis With an Intramedullary Antegrade Rod as a Salvage Procedure for the Chronically Infected Total Knee Arthroplasty.

机构信息

From the Department of Orthopaedic Surgery, Loyola University Medical Center, Maywood, IL (Dr. Brown); the Department of Orthopaedic Surgery, University of Rochester Medical Center, Orthopaedics & Rehabilitation, Rochester, NY (Dr. Balkissoon); OrthoCarolina, Sports Medicine Center, Atrium Health Musculoskeletal Institute (MSKI), Charlotte, NC (Dr. Saltzman); Anchorage Fracture & Orthopedic Clinic, Anchorage, AK (Dr. Haughom); UCSF Fresno, Fresno, CA (Dr. Li); the Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL (Dr. Levine); and the Department of Orthopaedic Surgery, Cadence Health, Winfield, IL (Dr. Sporer).

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2020 Sep;4(9):e20.00082-6. doi: 10.5435/JAAOSGlobal-D-20-00082.

Abstract

INTRODUCTION

Infection is a challenging complication after total knee arthroplasty (TKA) that is often treatable. However, recurrent infection may require resection, amputation, or arthrodesis. The purpose of this study was to evaluate the results of antegrade nailing with an intramedullary rod for the treatment of a chronically infected TKA.

METHODS

This study was a retrospective review of a consecutive series of 18 patients with chronically infected TKA treated with arthrodesis using a long antegrade intramedullary nail. There were 11 women and 7 men with an average age of 65 years and average body mass index of 33.8 kg/m. Patients had an average of 7.4 procedures before fusion, and mean follow-up was 50 months. One patient died in the early postoperative period, leaving 17 patients for evaluation. Fusion was defined radiographically as bony bridging of the joint surfaces visible on both anterior-posterior and lateral radiographs. Ambulatory ability, need for chronic antibiotic suppression, complications, and nail removal were recorded.

RESULTS

Sixteen of 17 patients (94%) underwent successful fusion. Ten of 17 patients (59%) continued to ambulate with 9 of these patients requiring an assist device and 7 of 17 patients (41%) predominantly used a wheelchair. Chronic antibiotic suppression was used in 13 of 17 patients (76%). Two patients required nail removal (one for pseudarthrosis and one for possible total hip arthroplasty) and overall 8 of 17 patients (47%) had a complication. Six of 18 patients (33%) died within 2 years of their fusion procedure.

DISCUSSION

Knee arthrodesis with an antegrade intramedullary nail is a viable treatment option for the chronically infected TKA. There was a high rate of successful fusion, along with a high rate of complications, mortality, and need for chronic antibiotic suppression.

CONCLUSION

Knee arthrodesis with a long IMN is a suitable treatment method as salvage for a chronically infected TKA, but patients should be counseled on the high rate of postoperative complications, poor ambulatory rate, likely need for suppressive antibiotics, and high mortality rate.

摘要

介绍

感染是全膝关节置换术后(TKA)的一种具有挑战性的并发症,通常可以治疗。然而,复发性感染可能需要切除、截肢或融合。本研究的目的是评估使用髓内棒逆行固定治疗慢性感染 TKA 的效果。

方法

这是一项回顾性连续系列研究,共 18 例慢性感染 TKA 患者接受关节融合术,使用长逆行髓内钉。11 名女性和 7 名男性,平均年龄 65 岁,平均体重指数 33.8kg/m2。患者在融合前平均有 7.4 次手术,平均随访 50 个月。1 例患者在术后早期死亡,其余 17 例患者进行了评估。融合定义为在前后位和侧位 X 线片上均可见关节面的骨桥形成。记录了患者的步行能力、是否需要慢性抗生素抑制、并发症和钉取出情况。

结果

17 例患者中 16 例(94%)融合成功。17 例患者中有 10 例(59%)可成功行走,其中 9 例需要辅助设备,17 例患者中有 7 例(41%)主要使用轮椅。17 例患者中有 13 例(76%)需要使用慢性抗生素抑制。2 例患者需要取出钉子(1 例为假关节,1 例为可能的全髋关节置换术),17 例患者中有 8 例(47%)发生了并发症。18 例患者中有 6 例(33%)在融合术后 2 年内死亡。

讨论

逆行髓内钉关节融合术是慢性感染 TKA 的一种可行治疗选择。融合成功率高,但并发症、死亡率和需要慢性抗生素抑制的发生率也较高。

结论

长髓内钉关节融合术是慢性感染 TKA 的一种合适的治疗方法,但应向患者说明术后并发症发生率高、步行能力差、可能需要抑制性抗生素和高死亡率等问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f624/7494141/8fcc739ed082/jagrr-4-e20.00082-g001.jpg

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