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新型抗凝剂(利伐沙班)使用继发的自发性出血性胆囊炎

Spontaneous haemorrhagic cholecystitis secondary to the use of novel anticoagulants (rivaroxaban).

作者信息

Kurian Merina, Lim Chee Khong, Kler Prabhjoyt, Chow Bing Lun, Chacko Cyril Jacob

机构信息

Royal Wolverhampton NHS Trust, London, UK.

Russells Hall Hospital NHS, London, UK.

出版信息

BJR Case Rep. 2023 Jan 11;9(6):20220128. doi: 10.1259/bjrcr.20220128. eCollection 2023 Nov.

Abstract

Haemorrhagic cholecystitis is a rare complication of acute cholecystitis. It carries a high risk of morbidity and mortality. Risk factors for haemorrhagic cholecystitis include cholelithiasis, trauma, malignancy and the use of anticoagulants. There have only been a few reported cases of haemorrhagic cholecystitis secondary to the use of novel oral anticoagulants (NOACs). The demographic transition of an ageing population will potentially increase the utilisation of NOACs. Therefore, the incidence of haemorrhagic cholecystitis secondary to NOACs will likely increase. Awareness and prompt diagnosis is paramount to avoid morbidity and mortality associated with haemorrhagic cholecystitis.

摘要

出血性胆囊炎是急性胆囊炎的一种罕见并发症。它具有较高的发病和死亡风险。出血性胆囊炎的危险因素包括胆石症、创伤、恶性肿瘤以及抗凝剂的使用。仅有少数关于新型口服抗凝剂(NOACs)导致出血性胆囊炎的报道病例。人口老龄化的人口结构转变可能会增加NOACs的使用。因此,NOACs导致的出血性胆囊炎的发病率可能会上升。提高认识并及时诊断对于避免与出血性胆囊炎相关的发病和死亡至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f75/10621570/886756aea66a/bjrcr.20220128.g001.jpg

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