Cosmetic Ingredient Review Senior Scientific Analyst/Writer.
Expert Panel for Cosmetic Ingredient Safety Member.
Int J Toxicol. 2024 Feb;43(1_suppl):64S-81S. doi: 10.1177/10915818231210792. Epub 2023 Nov 6.
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 10 -derived ingredients, which are most frequently reported to function in cosmetics as skin conditioning agents or antioxidants. The Panel reviewed the available data to determine the safety of these ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. The Panel was concerned about the presence of ginkgolic acid in cosmetics. Industry should use good manufacturing practices to limit impurities. The Panel concluded that 5 leaf-derived ingredients are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-sensitizing; data are insufficient to determine the safety of the remaining 5 ingredients under the intended conditions of use in cosmetic formulations.
专家组对 10 种植物衍生成分的安全性进行了评估，这些成分最常被报道在化妆品中作为皮肤调理剂或抗氧化剂发挥作用。专家组审查了现有数据，以确定这些成分的安全性。由于最终产品配方可能含有多种含有相同关注成分的植物，因此建议配方师了解这些成分，并避免达到可能对消费者造成危害的水平。专家组对化妆品中存在银杏酸表示关注。行业应采用良好的生产规范来限制杂质。专家组得出结论，在本安全性评估中描述的使用方法和浓度下，当配方为非致敏性时，5 种叶衍生成分是安全的；在化妆品配方中预期使用条件下，其余 5 种成分的安全性数据不足。
