Cosmetic Ingredient Review Senior Scientific Analyst/Writer.
Cosmetic Ingredient Review Expert Panel Member.
Int J Toxicol. 2021 Dec;40(3_suppl):53S-76S. doi: 10.1177/10915818211040477.
The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 33 flower- and leaf-derived ingredients, which are most frequently reported to function in cosmetics as fragrances and/or skin-conditioning agents. The Panel reviewed the available data to determine the safety of these ingredients. Because final product formulations may contain multiple botanicals, each containing similar constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. With flower- and leaf-derived ingredients, the Panel was concerned about the presence of the hydroperoxides of limonene and linalool in cosmetics. Industry should use good manufacturing practices to limit impurities that could be present in botanical ingredients. The Panel concluded that these ingredients are safe in the present practices of use and concentration when formulated to be non-irritating and non-sensitizing.
化妆品成分审查 (CIR) 专家小组 (Panel) 评估了 33 种花卉和叶类衍生成分的安全性，这些成分最常被报道在化妆品中作为香料和/或皮肤调理剂发挥作用。小组审查了现有数据，以确定这些成分的安全性。由于最终产品配方可能包含多种植物，每种植物都含有类似的关注成分，因此建议配方师注意这些成分，并避免达到可能对消费者造成危害的水平。对于花卉和叶类衍生成分，小组关注的是化妆品中柠檬烯和芳樟醇的氢过氧化物的存在。行业应采用良好的生产规范来限制植物成分中可能存在的杂质。小组得出结论，在配方中制成非刺激性和非致敏性时，这些成分在目前的使用和浓度实践中是安全的。
