San Francisco Veterans Affairs Health Care System, San Francisco, CA, USA.
Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
J Appl Gerontol. 2024 May;43(5):515-519. doi: 10.1177/07334648231210671. Epub 2023 Nov 6.
Adults aged 65+ are at highest risk for severe COVID-19 outcomes, and prior to the distribution of vaccines in the U.S., were strongly advised to quarantine at home to reduce risk of infection. This study examines how COVID-19 restrictions impacted various dementia risk factors and social determinants of health among older adults. Data came from the Systematic Multi-Domain Alzheimer's Risk Reduction Trial, a randomized controlled trial of a multi-domain intervention in higher-risk older adults (aged 70-89). A questionnaire was administered to participants ( = 156; 90.7% response rate) between May 2020 and March 2021. The data show a significant decline in social activity, physical activity, and mood among respondents. Compared to living with others, living alone was associated with worsened physical activity, diet, and subjective memory/thinking, adjusted for sex and age. These results suggest that the COVID-19 pandemic exacerbated several risk factors for dementia in older adults, particularly in those living alone.
65 岁以上的成年人患严重 COVID-19 的风险最高，在美国分发疫苗之前，强烈建议他们在家隔离以降低感染风险。本研究考察了 COVID-19 限制措施如何影响老年人的各种痴呆风险因素和健康的社会决定因素。数据来自系统多领域阿尔茨海默病风险降低试验，这是一项针对高风险老年人（70-89 岁）的多领域干预的随机对照试验。2020 年 5 月至 2021 年 3 月期间，向参与者（=156；90.7%的回复率）发放了一份问卷。数据显示，受访者的社会活动、体力活动和情绪明显下降。与与他人同住相比，独居与体力活动、饮食和主观记忆/思维的恶化有关，调整了性别和年龄。这些结果表明，COVID-19 大流行使老年人的几种痴呆风险因素恶化，尤其是独居者。
