美国流行地区军犬中球孢子菌属暴露情况。

Coccidioides spp. exposure among military working dogs in endemic regions of the United States.

机构信息

Department of Chemistry and Life Science United States Military Academy, Bartlett Hall, West Point, NY 10996, USA.

Department of Internal Medicine, Division of Infectious Diseases, University of California, Davis Health, Sacramento, CA 95817, USA.

出版信息

Med Mycol. 2023 Nov 6;61(11). doi: 10.1093/mmy/myad109.

DOI:10.1093/mmy/myad109

PMID:37935009

Abstract

Coccidioidomycosis is a fungal disease in arid regions of the United States that is predicted to expand with climate change. Cases in military personnel and military working dogs (MWDs) impact personnel readiness and result in healthcare costs. To examine Coccidioides exposure among MWDs, 276 banked serum samples were retrieved from dogs housed in California, Texas, Arizona, New Mexico, Nevada, and Utah. Using gel immunodiffusion, six (2.1%) specimens were IgG-positive and three (1.1%) were equivocally IgM-positive. The IgG-positive samples were from Arizona (2 [prevalence 8.0%]) and California (4 [3.7%]). These data will guide future efforts to study MWDs as sentinels for human coccidioidomycosis.

摘要

球孢子菌病是美国干旱地区的一种真菌病，预计随着气候变化而扩大。军人和军犬（MWD）中的病例会影响人员的战备状态并导致医疗保健费用增加。为了检查 MWD 中的球孢子菌属暴露情况，从加利福尼亚州、德克萨斯州、亚利桑那州、新墨西哥州、内华达州和犹他州的犬舍中检索了 276 份银行血清样本。使用凝胶免疫扩散法，有 6 份（2.1%）标本 IgG 阳性，3 份（1.1%）标本 IgM 阳性结果不确定。IgG 阳性样本来自亚利桑那州（2 例[流行率 8.0%]）和加利福尼亚州（4 例[流行率 3.7%]）。这些数据将指导未来研究 MWD 作为人类球孢子菌病的哨兵的工作。