Rosen I, Gordon W, Loyd M
Int J Radiat Oncol Biol Phys. 1986 Dec;12(12):2203-7. doi: 10.1016/0360-3016(86)90021-0.
A radioactive mold for treating skin was constructed by embedding ribbons of iridium-192 seeds in bolus material. The mold was designed to match the treatment area outlined on the patient's skin. Computer-assisted pre-planning was performed to optimize the seed strength, number of seeds, and spacing of ribbons. An outline of the treatment area was transferred to the surface of a uniform slab of tissue-equivalent bolus material 1.3 to 1.4 cm thick and planned locations for the ribbons were marked. Seeds were loaded into the bolus material at a depth to place the sources approximately 1.0 cm from the skin. The resulting mold was flexible enough to conform to the patient's skin and the seeds were so tightly confined within the bolus that there was no possibility of loss. Isodose distributions for the mold on a flat surface agreed well with preplans. A velcro strap and neck collar were used to attach the mold to the anterior portion of the patient's neck. For situations in which radioactive surface applicators are desirable, the use of iridium-192 seeds offers uniform dose within a highly individualized treatment area.
一种用于治疗皮肤的放射性模具是通过将铱 - 192 籽源带嵌入等效组织填充物中构建而成。该模具设计成与患者皮肤上勾勒出的治疗区域相匹配。进行了计算机辅助预规划以优化籽源强度、籽源数量和籽源带间距。将治疗区域的轮廓转移到一块厚度为 1.3 至 1.4 厘米的均匀等效组织填充物平板表面，并标记出籽源带的规划位置。将籽源装入填充物中，深度要使源距皮肤约 1.0 厘米。制成的模具柔韧性足以贴合患者皮肤，并且籽源被紧紧地限制在填充物内，不会有丢失的可能性。模具在平面上的等剂量分布与预规划结果吻合良好。使用尼龙搭扣带和颈圈将模具固定在患者颈部前部。对于需要放射性表面敷贴器的情况，使用铱 - 192 籽源可在高度个体化的治疗区域内提供均匀剂量。
