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患有主动脉瓣疾病和冠状动脉疾病的患者可从一种联合方法中获益,该方法通过右胸小切口进行主动脉瓣置换术并结合经皮冠状动脉介入治疗。

Patients with aortic valve disease and coronary artery disease can benefit from a hybrid approach combining aortic valve replacement through right minithoracotomy and percutaneous coronary intervention.

作者信息

Rzucidło-Resil Jolanta Maria, Stoliński Jarosław, Musiał Robert, Sobczyński Robert, Plicner Dariusz

机构信息

Department of Noninvasive Cardiovascular Laboratory, John Paul II Hospital, Krakow, Poland.

Department of Cardiovascular Surgery and Transplantology, John Paul II Hospital, Krakow, Poland.

出版信息

Kardiochir Torakochirurgia Pol. 2023 Sep;20(3):146-154. doi: 10.5114/kitp.2023.131954. Epub 2023 Oct 30.

Abstract

INTRODUCTION

Minimally invasive and hybrid procedures for patients with aortic valve pathology and coronary artery disease are innovative solutions.

AIM

To report the results of hybrid aortic valve replacement through right anterior minithoracotomy (RT-AVR)/percutaneous coronary intervention (PCI) and conventional aortic valve replacement (AVR)/coronary artery bypass grafting (CABG) surgery for patients with aortic valve and coronary artery disease.

MATERIAL AND METHODS

Analysis of prospectively gathered data of 187 patients - 86 hybrid and 101 conventional procedures. For 21 patients, RT-AVR was followed by PCI during the same session, and for 65 patients RT-AVR was performed within 90 days of PCI.

RESULTS

Hospital mortality in the AVR/CABG and RT-AVR/PCI groups was 3.0% and 1.2%, respectively ( = 0.237). Complications occurred in 18.6% of patients in the RT-AVR/PCI group and 33.7% in the AVR/CABG group ( = 0.020). Two-stage RT-AVR/PCI was performed due to ACS (100%); one-stage was due to the intention to perform a minimally invasive procedure instead of AVR/CABG (71.4%) or due to replacing CABG with PCI because of a lack of vascular grafts for CABG (19.1%). In 38.5% of patients from the two-stage subgroup, antiplatelet therapy was stopped before RT-AVR, 32.3% of patients from the two-stage subgroup were on single, and 29.2% on dual antiplatelet therapy until RT-AVR, which had no influence on postoperative blood requirements or postoperative myocardial infarction ( = 0.410 and = 0.077, respectively).

CONCLUSIONS

The hybrid procedure presented in our series showed similar mortality and morbidity results and may be an alternative to conventional AVR and CABG through full sternotomy in selected patients.

摘要

引言

针对主动脉瓣病变和冠状动脉疾病患者的微创及杂交手术是创新解决方案。

目的

报告采用右前小切口杂交主动脉瓣置换术(RT-AVR)/经皮冠状动脉介入治疗(PCI)以及传统主动脉瓣置换术(AVR)/冠状动脉旁路移植术(CABG)治疗主动脉瓣和冠状动脉疾病患者的结果。

材料与方法

对187例患者的前瞻性收集数据进行分析——86例杂交手术和101例传统手术。21例患者在同一会诊期间先进行RT-AVR,随后进行PCI,65例患者在PCI后90天内进行RT-AVR。

结果

AVR/CABG组和RT-AVR/PCI组的医院死亡率分别为3.0%和1.2%(P = 0.237)。RT-AVR/PCI组18.6%的患者发生并发症,AVR/CABG组为33.7%(P = 0.020)。因急性冠状动脉综合征(ACS)进行两阶段RT-AVR/PCI的占100%;一阶段手术是由于打算进行微创手术而非AVR/CABG(71.4%),或因缺乏用于CABG的血管移植物而用PCI替代CABG(19.1%)。在两阶段亚组的38.5%患者中,RT-AVR前停用抗血小板治疗,两阶段亚组32.3%的患者采用单一抗血小板治疗,29.2%的患者在RT-AVR前采用双重抗血小板治疗,这对术后用血需求或术后心肌梗死均无影响(分别为P = 0.410和P = 0.077)。

结论

我们系列研究中的杂交手术显示出相似的死亡率和发病率结果,对于部分选定患者而言,可能是通过全胸骨切开术进行传统AVR和CABG的替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c15/10626405/db7b2fc9593c/KITP-20-51618-g001.jpg

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