五十载金属酶学研究。
Five decades of metalloenzymology.
机构信息
Departments of Microbiology & Molecular Genetics and Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI, United States.
出版信息
Enzymes. 2023;54:71-105. doi: 10.1016/bs.enz.2023.03.001. Epub 2023 Mar 30.
Abstract
Metalloenzymes have been detailed in The Enzymes since its inception over half a century ago. Here, I review selected metal-containing enzyme highlights from early chapters in this series and I describe advances made since those contributions. Three topics are emphasized: nickel-containing enzymes, Fe(II)/2-oxoglutarate-dependent oxygenases, and enzymes containing non-canonical iron-sulfur clusters.
摘要
半个多世纪前《酶学》创刊以来，一直详细介绍金属酶。在这里，我回顾了该系列早期章节中选定的含金属酶的要点，并描述了自这些贡献以来取得的进展。强调了三个主题：含镍酶、Fe(II)/2-氧代戊二酸依赖性加氧酶和含有非典型铁硫簇的酶。
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