Challacombe D N, Wheeler E E, Campbell P E
J Pediatr Gastroenterol Nutr. 1986 Nov-Dec;5(6):887-91. doi: 10.1097/00005176-198611000-00011.
Morphometric studies and eosinophil counts in the lamina propria of the duodenal mucosa have been performed in patients with chronic nonspecific diarrhoea and with persistent diarrhoea due to a cow's milk allergy, using a semiautomatic image analysing system. The results have shown that the mean eosinophil count was significantly higher in both of these groups of patients compared with a control group (p less than 0.001), and some of the patients with chronic nonspecific diarrhoea had partial villous flattening. These findings in patients with chronic nonspecific diarrhoea could be related to the pathogenesis of this disorder.
利用半自动图像分析系统，对患有慢性非特异性腹泻以及因牛奶过敏导致持续性腹泻的患者的十二指肠黏膜固有层进行了形态测量研究和嗜酸性粒细胞计数。结果显示，与对照组相比，这两组患者的平均嗜酸性粒细胞计数均显著更高（p小于0.001），并且一些慢性非特异性腹泻患者存在部分绒毛变平的情况。慢性非特异性腹泻患者的这些发现可能与该疾病的发病机制有关。
