School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, 112303, Taiwan.
Department of Colorectal Surgery, Cathay General Hospital, Taipei City, 10630, Taiwan.
Eur J Oncol Nurs. 2023 Dec;67:102431. doi: 10.1016/j.ejon.2023.102431. Epub 2023 Oct 30.
To test the efficacy of a self-management program based on acceptance and commitment therapy on quality of life, emotional distress, fatigue, physical activity, and fruit and vegetable intake in patients with colorectal cancer.
The study was a randomized controlled trial. A sample of 156 patients with colorectal cancer (stage I-III) was recruited by convenience sampling and participants were allocated randomly assigned to control or intervention groups. The intervention included a colorectal cancer self-management information booklet, two personal skills training sessions, and 12 follow-up telephone calls. The control group received health education leaflets. Outcome variables were assessed in both groups at baseline and every two months thereafter during the six-month follow-up period.
The mean age of participants was 62 years (range: 30-89 years). Generalized estimation equations analyses revealed significant differences over time in changes in anxiety (β = -2.22, p = 0.001), depression (β = -1.48, p = 0.033), fatigue (β = 4.46, p = 0.001), physical and functional measures (β = 6.16, p = 0.005), and colorectal-cancer-specific quality of life (β = 7.45, p = 0.012). However, there were no significant differences in changes in physical activity or fruit and vegetable intake over time.
The self-management skills provided by oncology nurses, including symptom management, psychological adjustment, and relaxation exercises, help colorectal cancer patients to overcome the challenges of cancer survivorship, accelerate their recovery, and improve their quality of life.
NCT03853278 registered on ClinicalTrials.gov.
检验基于接纳与承诺疗法的自我管理方案对结直肠癌患者生活质量、情绪困扰、疲劳、身体活动及果蔬摄入的疗效。
这是一项随机对照试验。通过便利抽样招募了 156 例结直肠癌（I-III 期）患者作为研究样本，将参与者随机分配到对照组或干预组。干预措施包括结直肠癌自我管理信息手册、两次个人技能培训课程和 12 次随访电话。对照组接受健康教育传单。在 6 个月的随访期间，两组均在基线和此后每两个月评估结局变量。
参与者的平均年龄为 62 岁（范围：30-89 岁）。广义估计方程分析显示，焦虑（β=-2.22，p=0.001）、抑郁（β=-1.48，p=0.033）、疲劳（β=4.46，p=0.001）、身体和功能测量（β=6.16，p=0.005）以及结直肠癌特异性生活质量（β=7.45，p=0.012）方面的变化在时间上有显著差异。然而，身体活动或果蔬摄入方面的变化在时间上没有显著差异。
肿瘤护士提供的自我管理技能，包括症状管理、心理调整和放松练习，有助于结直肠癌患者克服癌症生存挑战，加速康复，提高生活质量。
NCT03853278，在 ClinicalTrials.gov 注册。
