Cheng E R, Okoye M I
J Natl Med Assoc. 1986 Nov;78(11):1073-8.
One hundred patients aged 20 years and younger, admitted to Hurley Medical Center during a ten-year period for treatment of acute or chronic cholecystitis with or without cholelithiasis, were reviewed. Results demonstrated an increasing incidence of pediatric cases compared with previous reports, a predominance in parous teenagers, and only an 8 percent association with hemolytic diseases. The clinical presentation is very similar to that of adults. Maintaining a high index of suspicion in addition to the use of diagnostic aids such as cholecystogram, ultrasonography, and hepatobiliary imaging with technetium 99m PIPIDA (paraisopropylacetanilide iminoacetate) should lead to the diagnosis of gallbladder disease even at a very early age. Elective cholecystectomy in the stable patient is the treatment of choice, and any delays in the diagnosis and treatment will increase morbidity and mortality considerably.
对100名20岁及以下因急慢性胆囊炎伴或不伴胆结石而在十年期间入住赫尔利医疗中心的患者进行了回顾。结果显示,与先前报告相比,儿科病例的发病率有所增加,经产妇青少年占主导,且仅8%与溶血性疾病有关。临床表现与成年人非常相似。除了使用胆囊造影、超声检查和锝99m PIPIDA(对异丙基乙酰苯胺亚氨基乙酸酯)肝胆显像等诊断辅助手段外,保持高度怀疑指数应能在极早期诊断出胆囊疾病。对于病情稳定的患者,择期胆囊切除术是首选治疗方法,诊断和治疗的任何延迟都会显著增加发病率和死亡率。