Department of Epidemiology, School of Public Health, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
J Affect Disord. 2024 Feb 1;346:214-220. doi: 10.1016/j.jad.2023.11.029. Epub 2023 Nov 11.
There are limited data on the association between secondhand smoke (SHS) exposure across the life course and depressive symptoms among older adults. We aimed to investigate the association of childhood household SHS exposure, adulthood household SHS exposure, lifetime social SHS exposure, and their coexistence with depressive symptoms in older adults.
Data were from the 2011-2012 and 2014 waves of the Chinese Longitudinal Healthy Longevity Survey. About 4000 participants (aged 60 years or older) were recruited in a randomly selected half of the counties and cities in China. Data on SHS exposure, past-year depressive symptoms, and covariates were collected using a questionnaire. The chi-square test (for categorical variables) and t-test (for continuous variables) were used to assess differences in the participant characteristics across groups of SHS exposures. We estimated the odds ratios (ORs) and 95 % confidence intervals (CIs) of depressive symptom according to different types of SHS exposure.
Childhood household SHS exposure (OR = 1.42, 95%CI = 1.22-1.66), adulthood household SHS exposure (OR = 1.41, 95%CI = 1.21-1.63) and lifetime social SHS exposure (OR = 1.35, 95%CI = 1.14-1.58) were associated with higher odds of depressive symptoms. Additionally, those with a higher SHS exposure score had higher odds of depressive symptoms (1 point: OR = 1.56, 95%CI = 1.22-2.00; 2 points: OR = 1.77, 95%CI = 1.39-2.25; 3 points: OR = 1.83, 95%CI = 1.45-2.31). The results were similar when stratified by lifetime nonsmoking, former smoking, and current smoking.
Retrospective design may introduce recall bias.
SHS exposure was associated with higher odds of depressive symptoms in older adults, with the effect seeming to be addictive.
关于一生中二手烟（SHS）暴露与老年人抑郁症状之间的关联，数据有限。我们旨在调查儿童家庭 SHS 暴露、成年家庭 SHS 暴露、终生社会 SHS 暴露及其与老年人抑郁症状共存的关系。
数据来自 2011-2012 年和 2014 年中国纵向健康长寿调查的波次。大约 4000 名（年龄在 60 岁或以上）参与者在中国随机选择的一半县和市被招募。使用问卷收集 SHS 暴露、过去一年的抑郁症状和协变量的数据。使用卡方检验（用于分类变量）和 t 检验（用于连续变量）来评估 SHS 暴露组之间参与者特征的差异。我们根据不同类型的 SHS 暴露估计了抑郁症状的比值比（OR）和 95%置信区间（CI）。
儿童家庭 SHS 暴露（OR=1.42，95%CI=1.22-1.66）、成年家庭 SHS 暴露（OR=1.41，95%CI=1.21-1.63）和终生社会 SHS 暴露（OR=1.35，95%CI=1.14-1.58）与抑郁症状的高几率相关。此外，暴露于较高 SHS 评分的人患抑郁症状的几率更高（1 分：OR=1.56，95%CI=1.22-2.00；2 分：OR=1.77，95%CI=1.39-2.25；3 分：OR=1.83，95%CI=1.45-2.31）。当按终生不吸烟、曾经吸烟和当前吸烟分层时，结果相似。
回顾性设计可能会引入回忆偏倚。
SHS 暴露与老年人抑郁症状的几率增加有关，这种效应似乎是上瘾的。
