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一例大疱性系统性红斑狼疮：诊断挑战与临床意义

A case of bullous systemic lupus erythematosus: Diagnostic challenges and clinical implications.

作者信息

Bhandari Samikchhya Keshary, Gautam Naveen, Pandeya Anupama, Jha Saket

机构信息

Tribhuvan University Teaching Hospital Kathmandu Nepal.

Tribhuvan University Teaching Hospital, Internal Medicine, Rheumatology Kathmandu Nepal.

出版信息

Clin Case Rep. 2023 Nov 8;11(11):e8167. doi: 10.1002/ccr3.8167. eCollection 2023 Nov.

DOI:10.1002/ccr3.8167
PMID:37953897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10632556/
Abstract

Skin involvement in systemic lupus erythematosus (SLE) is common. Bullous lesions in SLE patients are usually due to other autoimmune conditions or rarely, due to lupus itself. Bullous SLE is rare blistering disorder characterized by subepidermal blisters. We, hereby, present a case of bullous SLE in a 24-year-old female who responded well to systemic glucocorticoids, mycophenolate mofetil, and dapsone.

摘要

皮肤受累在系统性红斑狼疮（SLE）中很常见。SLE患者的大疱性皮损通常归因于其他自身免疫性疾病，或极少情况下归因于狼疮本身。大疱性SLE是一种罕见的以表皮下水疱为特征的水疱性疾病。在此，我们报告一例24岁女性的大疱性SLE病例，该患者对系统性糖皮质激素、霉酚酸酯和氨苯砜反应良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/5ab1c31d94ff/CCR3-11-e8167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/19c3372c6adc/CCR3-11-e8167-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/f8b748ca0ded/CCR3-11-e8167-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/5bd46cd28a1e/CCR3-11-e8167-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/5ab1c31d94ff/CCR3-11-e8167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/19c3372c6adc/CCR3-11-e8167-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/f8b748ca0ded/CCR3-11-e8167-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/5bd46cd28a1e/CCR3-11-e8167-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/11d7/10632556/5ab1c31d94ff/CCR3-11-e8167-g002.jpg

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Autoimmune Dis. 2022 Jul 19;2022:9388745. doi: 10.1155/2022/9388745. eCollection 2022.
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Bullous systemic lupus erythematosus - a case report.
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A 12-year retrospective review of bullous systemic lupus erythematosus in cutaneous and systemic lupus erythematosus patients.对皮肤型和系统性红斑狼疮患者中大疱性系统性红斑狼疮的12年回顾性研究。
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Bullous Systemic Lupus Erythematosus and Lupus Nephritis in a Young Girl.一名年轻女孩的大疱性系统性红斑狼疮和狼疮性肾炎
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