Hong Yuqin, Zhong Lijuan, Lv Xue, Liu Qiao, Fu Langzhou, Zhou Daiquan, Yu Na
Department of Radiology, The Third Affiliated Hospital of Chongqing Medical University (Gener Hospital), Chongqing, China.
Department of Radiology, The People's Hospital of Leshan, Leshan, China.
Front Mol Biosci. 2023 Oct 25;10:1284549. doi: 10.3389/fmolb.2023.1284549. eCollection 2023.
Gastrointestinal (GI) cancer is the leading cause of cancer-related deaths worldwide. Computed tomography (CT) is an important auxiliary tool for the diagnosis, evaluation, and prognosis prediction of gastrointestinal tumors. Spectral CT is another major CT revolution after spiral CT and multidetector CT. Compared to traditional CT which only provides single-parameter anatomical diagnostic mode imaging, spectral CT can achieve multi-parameter imaging and provide a wealth of image information to optimize disease diagnosis. In recent years, with the rapid development and application of spectral CT, more and more studies on the application of spectral CT in the characterization of GI tumors have been published. For this review, we obtained a substantial volume of literature, focusing on spectral CT imaging of gastrointestinal cancers, including esophageal, stomach, colorectal, liver, and pancreatic cancers. We found that spectral CT can not only accurately stage gastrointestinal tumors before operation but also distinguish benign and malignant GI tumors with improved image quality, and effectively evaluate the therapeutic response and prognosis of the lesions. In addition, this paper also discusses the limitations and prospects of using spectral CT in GI cancer diagnosis and treatment.
胃肠道（GI）癌是全球癌症相关死亡的主要原因。计算机断层扫描（CT）是胃肠道肿瘤诊断、评估和预后预测的重要辅助工具。光谱CT是继螺旋CT和多排探测器CT之后的又一次重大CT革命。与仅提供单参数解剖诊断模式成像的传统CT相比，光谱CT可以实现多参数成像，并提供丰富的图像信息以优化疾病诊断。近年来，随着光谱CT的快速发展和应用，越来越多关于光谱CT在胃肠道肿瘤特征描述中的应用研究得以发表。在本综述中，我们获取了大量文献，重点关注胃肠道癌的光谱CT成像，包括食管癌、胃癌、结直肠癌、肝癌和胰腺癌。我们发现，光谱CT不仅可以在术前准确对胃肠道肿瘤进行分期，还能以更高的图像质量区分胃肠道良性和恶性肿瘤，并有效评估病变的治疗反应和预后。此外，本文还讨论了使用光谱CT进行胃肠道癌诊断和治疗的局限性及前景。
