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镰状细胞病患者腹腔镜胆囊切除术后因胆源性植物粪石异常形成导致的多发性小肠梗阻:一例报告及非典型手术方法

Multiple small bowel obstructions due to unusual formation of biliary phytobezoars following laparoscopic cholecystectomy in a sickler patient: A case report, an atypical surgical approach.

作者信息

Al-Abbadi Hatim Ali

机构信息

King Abdulaziz University Hospital, Faculty of Medicine, King Abdulaziz University, Saudi Arabia.

出版信息

Int J Surg Case Rep. 2023 Dec;113:109013. doi: 10.1016/j.ijscr.2023.109013. Epub 2023 Nov 10.

DOI:10.1016/j.ijscr.2023.109013
PMID:37956495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10661604/
Abstract

INTRODUCTION & IMPORTANCE: Bezoar formation in gastrointestinal tract is relatively a rare condition. A phytobezoar is the most common type of bezoar (Kement et al., 2012 [6]). Biliary phytobezoar is an extremely rare condition and is usually reported in patients had previous biliary procedures or in presence of bilioenteric fistula (Albogami et al., 2018; Kement et al., 2012; Kim et al., 2006 [2, 6, 7]).

CASE PRESENTATION

35-year-old female with sickle cell anemia (SCA). On 2003 she had gallstones (GS) and obstructive jaundice. She was treated at that time by endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy with stent insertion, followed by laparoscopic cholecystectomy (LC). Two years afterwards she had open appendectomy for acute appendicitis. Six months afterward, she suffered several episodes of small bowel obstructions (SBO) for several years. Later, it was discovered due to unusual formation of primary gallstones and subsequent development of biliary phytobezoars accumulated in the terminal ileum causing SBO.

CLINICAL DISCUSSION

We are presenting an extremely rare case who developed biliary phytobezoars formation in the absence of a bilioenteric fistula leading to multiple small bowel obstructions. The origin of the gallstones was primary type. The surgical approach was limited right hemicolectomy solved her problem completely until the date of this publication.

CONCLUSION

The nature of the disease adding higher risk of morbidity. Management of sicklers with surgical conditions should be individualized. Sicklers with asymptomatic gallstones should have early LC before complications begin. Because anticipated complications carry significant morbidity. The advances in surgical technology and better awareness of the pathophysiology provided an improved and better outcome.

摘要

引言与重要性

胃肠道内形成粪石是一种相对罕见的情况。植物性粪石是最常见的粪石类型(凯门特等人,2012年[6])。胆源性植物性粪石极为罕见,通常见于既往有胆道手术史或存在胆肠瘘的患者(阿尔博加米等人,2018年;凯门特等人,2012年;金等人,2006年[2,6,7])。

病例介绍

一名35岁患有镰状细胞贫血(SCA)的女性。2003年,她患有胆结石(GS)和梗阻性黄疸。当时接受了内镜逆行胰胆管造影(ERCP)、括约肌切开术及支架置入,随后进行了腹腔镜胆囊切除术(LC)。两年后,她因急性阑尾炎接受了开腹阑尾切除术。六个月后,她出现了数年的多次小肠梗阻(SBO)发作。后来发现,由于原发性胆结石异常形成以及随后胆源性植物性粪石在回肠末端积聚导致了SBO。

临床讨论

我们报告了一例极为罕见的病例,该病例在无胆肠瘘的情况下发生胆源性植物性粪石形成并导致多次小肠梗阻。胆结石的起源为原发性。手术方式为有限的右半结肠切除术,直至本文发表时已完全解决了她的问题。

结论

该疾病的性质增加了更高的发病风险。患有外科疾病的镰状细胞贫血患者的治疗应个体化。无症状胆结石的镰状细胞贫血患者应在并发症出现前尽早进行LC。因为预期的并发症会带来显著的发病率。手术技术的进步和对病理生理学的更好认识带来了改善且更好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/b064fddc168c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/ad6bdc213432/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/aa6667820afe/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/317d69d317e7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/b064fddc168c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/ad6bdc213432/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/aa6667820afe/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/317d69d317e7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3511/10661604/b064fddc168c/gr4.jpg

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