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T3期梨状窦癌临床诊断与组织病理学诊断之间的差异

Discrepancies between clinical and histopathologic diagnoses in T3 pyriform sinus cancer.

作者信息

Tani M, Amatsu M

出版信息

Laryngoscope. 1987 Jan;97(1):93-6. doi: 10.1288/00005537-198701000-00018.

DOI:10.1288/00005537-198701000-00018
PMID:3796180
Abstract

The various ways in which pyriform sinus cancer extends to laryngeal structures were analyzed by whole-organ serial-sectioning. The problems regarding vocal cord fixation (T3) by this cancer are discussed. This study found that vocal cord fixation in pyriform sinus cancer is due mainly to the involvement of the intrinsic laryngeal muscles and not to the involvement of the arytenoid cartilage or the cricoarytenoid joint. A tumor originating in the medial wall tends to extend medially and to invade the intrinsic laryngeal muscles. This causes vocal cord fixation (T3) before classification as T2. However, a tumor originating in the lateral wall extends laterally beyond the thyroid ala (T4) with a mobile cord. Therefore, it is suggested that the T classification of the vocal cord fixation (T3) of pyriform sinus cancer may not reflect the actual cancer involvement.

摘要

通过全器官连续切片分析了梨状窝癌扩展至喉部结构的各种方式。讨论了该癌症导致声带固定(T3)的相关问题。本研究发现,梨状窝癌中的声带固定主要是由于喉内肌受累,而非杓状软骨或环杓关节受累。起源于内侧壁的肿瘤倾向于向内侧扩展并侵犯喉内肌。这在分类为T2之前就导致了声带固定(T3)。然而,起源于外侧壁的肿瘤在声带可活动的情况下向外侧延伸超出甲状腺翼(T4)。因此,提示梨状窝癌声带固定(T3)的T分类可能无法反映实际的癌症累及情况。

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