Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China.
Environ Sci Pollut Res Int. 2023 Dec;30(58):121823-121833. doi: 10.1007/s11356-023-30942-6. Epub 2023 Nov 14.
Children aged 3-6 years undergo a critical stage of growth and development and are irreversibly affected by their iodine status. In order to reveal iodine status in preschool children, we detected iodine concentrations in urine samples from 1382 children aged 3-6 years based on a cross-sectional study. The median urinary iodine concentration (UIC) of children was 193.36 μg/L and was 336.96 μg/g·Cr corrected for creatinine. The study developed a link between dietary habits and iodine status, revealing that regular calcium supplement (OR: 1.79, (95% CI: 1.03, 3.12)) increased deficiency risk, while moderate seafood consumption (OR: 0.60, (95% CI: 0.38, 0.95)) decreased it. Additionally, modest intake of shellfish (OR: 0.58, (95% CI: 0.33, 1.00)), vegetables (OR: 0.61, (95% CI: 0.38, 0.97)), and eggs (OR: 0.53, (95% CI: 0.30, 0.95)) was found to protect against excess iodine. The findings underline the importance of balanced diets and various nutrients' roles in preschoolers' iodine status.
3-6 岁儿童正处于生长发育的关键阶段,其碘营养状况会对其产生不可逆转的影响。为了揭示学龄前儿童的碘营养状况,我们基于横断面研究,检测了 1382 名 3-6 岁儿童的尿碘浓度。儿童的尿碘中位数(UIC)为 193.36μg/L,用肌酐校正后为 336.96μg/g·Cr。该研究还揭示了饮食习惯与碘营养状况之间的关系,表明定期补钙(OR:1.79,(95%CI:1.03,3.12))会增加碘缺乏的风险,而适量摄入海鲜(OR:0.60,(95%CI:0.38,0.95))则会降低风险。此外,适度摄入贝类(OR:0.58,(95%CI:0.33,1.00))、蔬菜(OR:0.61,(95%CI:0.38,0.97))和鸡蛋(OR:0.53,(95%CI:0.30,0.95))也可预防碘过量。这些发现强调了均衡饮食和各种营养素在学龄前儿童碘营养状况中的重要作用。