日粮维生素D和钙对雏鸡骨生长板赖氨酰氧化酶活性的影响。

Effects of dietary vitamin D and calcium on lysyl oxidase activity in chick bone metaphyses.

作者信息

Gonnerman W A, Toverud S U, Ramp W K, Mechanic G L

出版信息

Proc Soc Exp Biol Med. 1976 Mar;151(3):453-6. doi: 10.3181/00379727-151-39233.

Abstract

Activity of lysyl oxidase, an enzyme responsible for production of aldehydic precursors for lysine-derived collagen crosslinks, was measured in tibial metaphyses from chicks receiving different dietary levels of vitamin D and Ca for 2 weeks after hatching. Enzyme activities were increased twofold in D-deficient chicks compared to activities from chicks receiving control levels of vitamin D. Addition of Ca to the D-deficient diet had no effect on lysyl oxidase activity. It is suggested that vitamin D may play a role in the age-related decrease in lysyl oxidase activity that normally occurs in chick bone.

摘要

赖氨酰氧化酶是一种负责生成赖氨酸衍生的胶原蛋白交联醛前体的酶，在孵化后2周接受不同饮食水平维生素D和钙的雏鸡胫骨干骺端中测量了该酶的活性。与接受对照水平维生素D的雏鸡相比，维生素D缺乏的雏鸡酶活性增加了两倍。向维生素D缺乏的饮食中添加钙对赖氨酰氧化酶活性没有影响。提示维生素D可能在雏鸡骨骼中正常发生的与年龄相关的赖氨酰氧化酶活性降低中起作用。