Singh Jasbir, Saini Shubham, Chauhan Ravish K, Bhardwaj Pallavi, Kumar Ashwani
Department of Chemistry, Baba Mastnath University, Rohtak, 124021, India.
Bharat Institute of Pharmacy Degree Course, Pehladpur, Babain-Kurukshetra, 136132, India.
J Fluoresc. 2025 Jan;35(1):21-28. doi: 10.1007/s10895-023-03491-x. Epub 2023 Nov 16.
Here, we developed a novel isoniazid based fluorescent probe (E)-N'-(thiophen-2-ylmethylene)isonicotinohydrazide (TINH) through simple condensation reaction and employed for selective detection of Pd ions with a low detection limit of 4.102 × 10 M. Among the many existing cations, TINH bound Pd ions with an association affinity of 9.794 × 10 M. Adding Pd ions to ligand solution increased the absorption intensity in UV-Visible and quenched the emission intensity in fluorescence spectroscopic experiments. More importantly, this TINH complexed to Pd ions in 1:1 stoichiometric ratio. To evaluate the stability of complexed system, pH experiments has been performed. The binding insights among the ligand and Pd ions has been confirmed by IR spectroscopic and MASS spectrometric methods. Additionally, TINH also applied to real water samples for the identification and measurement of Pd ions. Hence, this system could be highly applicable for detection of Pd ions in environmental and industrial samples with in low detection range.
在此，我们通过简单的缩合反应开发了一种基于异烟肼的新型荧光探针（E）-N'-（噻吩-2-基亚甲基）异烟酰肼（TINH），并用于选择性检测钯离子，检测限低至4.102×10⁻⁸ M。在众多现有阳离子中，TINH与钯离子结合，缔合亲和力为9.794×10⁷ M。在荧光光谱实验中，向配体溶液中加入钯离子会增加紫外-可见吸收强度并淬灭发射强度。更重要的是，这种TINH与钯离子以1:1的化学计量比络合。为了评估络合体系的稳定性，进行了pH实验。通过红外光谱和质谱方法证实了配体与钯离子之间的结合情况。此外，TINH还应用于实际水样中钯离子的鉴定和测量。因此，该体系在低检测范围内可高度适用于环境和工业样品中钯离子的检测。
