Henan Institute of Medical and Pharmaceutical Sciences & BGI College, Zhengzhou University, Zhengzhou, China.
Nat Prod Res. 2024 Dec;38(23):4191-4195. doi: 10.1080/14786419.2023.2280791. Epub 2023 Nov 16.
The bioactivities of crude polysaccharides from leaves (L-Ps) and flowers (F-Ps) of (Maxim.) P. D. Cantino were studied, and the characteristics of purified fractions were analysed by HPLC, HP-GPC and NMR. L-Ps exhibited strong DPPH radical scavenging activity (IC value of 251.53 ± 4.62 μg/mL) and tyrosinase inhibition (IC value of 163.52 ± 2.59 μg/mL). However, the maximum moisture absorption (74.67 ± 1.53%) and retention (68.00 ± 3.61%) abilities were observed in F-Ps. Two main fractions separated by DEAE-Sepharose fast flow column from L-Ps were eluted with 0.1 and 0.3 M NaCl, while one main fraction from F-Ps was eluted with 0.1 M NaCl. Purified fractions were obviously different in monosaccharide composition, molecular weight and H NMR and C NMR spectra. Therefore, the current manuscript can provide an important evidence for the potential development of L-Ps and F-Ps as promising ingredients in cosmetics industry.
研究了(Maxim.)P. D. Cantino的叶(L-Ps)和花(F-Ps)粗多糖的生物活性,并通过 HPLC、HP-GPC 和 NMR 分析了纯化部分的特性。L-Ps 表现出较强的 DPPH 自由基清除活性(IC 值为 251.53±4.62μg/mL)和酪氨酸酶抑制活性(IC 值为 163.52±2.59μg/mL)。然而,F-Ps 具有最大的吸湿能力(74.67±1.53%)和保水能力(68.00±3.61%)。从 L-Ps 中用 DEAE-Sepharose 快速流动柱分离得到的两个主要部分分别用 0.1 和 0.3 M NaCl 洗脱,而 F-Ps 的一个主要部分用 0.1 M NaCl 洗脱。纯化部分在单糖组成、分子量和 H NMR 和 C NMR 图谱上明显不同。因此,本研究为 L-Ps 和 F-Ps 作为化妆品工业有前途的成分的潜在开发提供了重要证据。