Division of Allergy and Immunology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York 10029, USA; Department of Pediatrics, Jaffe Food Allergy Institute, 10540 Avenue K, Brooklyn, NY 11236-3018, USA.
Division of Allergy and Immunology, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York 10029, USA; Department of Pediatrics, Jaffe Food Allergy Institute, 10540 Avenue K, Brooklyn, NY 11236-3018, USA.
Immunol Allergy Clin North Am. 2024 Feb;44(1):75-83. doi: 10.1016/j.iac.2023.07.003. Epub 2023 Aug 7.
The role of environmental factors including climate change and consequent influences of air pollution on food allergy remains less explored compared with impacts on allergic rhinitis and asthma. In this review, we discuss the epithelial barrier hypothesis as a proposed mechanism of food allergy development that may be relevant in this context. We also discuss existing studies that provide insight into the intricate relationship between food allergy and climate-related environmental factors.
与变应性鼻炎和哮喘相比,环境因素(包括气候变化和随之而来的空气污染影响)在食物过敏中的作用仍较少被探索。在这篇综述中,我们讨论了上皮屏障假说作为食物过敏发展的一种可能相关机制,该假说可能在这方面具有相关性。我们还讨论了现有的研究,这些研究深入探讨了食物过敏与气候相关环境因素之间的复杂关系。