Division of Respiratory and Allergic Diseases, Department of Chest Diseases, High Specialty A. Cardarelli Hospital, Napoli, Italy and Medical School of Specialization in Respiratory Diseases, University of Naples Federico II.
First Division of Pneumology, High Specialty Hospital 'V. Monaldi' and University 'Federico II' Medical School Naples, Napoli, Italy.
Curr Opin Pediatr. 2023 Jun 1;35(3):356-361. doi: 10.1097/MOP.0000000000001237. Epub 2023 Mar 14.
Respiratory allergy correlates strictly with air pollution and climate change. Due to climate change, the atmospheric content of trigger factors such as pollens and moulds increase and induce rhinitis and asthma in sensitized patients with IgE-mediated allergic reactions.Pollen allergy is frequently used to evaluate the relationship between air pollution and allergic respiratory diseases. Pollen allergens trigger the release of immunomodulatory and pro-inflammatory mediators and accelerate the onset of sensitization to respiratory allergens in predisposed children and adults. Lightning storms during pollen seasons can exacerbate respiratory allergy and asthma not only in adults but also in children with pollinosis. In this study, we have focalized the trigger (chemical and biologic) factors of outdoor air pollution.
Environmental pollution and climate change have harmful effects on human health, particularly on respiratory system, with frequent impact on social systems.Climate change is characterized by physic meteorological events inducing increase of production and emission of anthropogenic carbon dioxide (CO 2 ) into the atmosphere. Allergenic plants produce more pollen as a response to high atmospheric levels of CO 2 . Climate change also affects extreme atmospheric events such as heat waves, droughts, thunderstorms, floods, cyclones and hurricanes. These climate events, in particular thunderstorms during pollen seasons, can increase the intensity of asthma attacks in pollinosis patients.
Climate change has important effects on the start and pathogenetic aspects of hypersensitivity of pollen allergy. Climate change causes an increase in the production of pollen and a change in the aspects increasing their allergenic properties. Through the effects of climate change, plant growth can be altered so that the new pollen produced are modified affecting more the human health. The need for public education and adoption of governmental measures to prevent environmental pollution and climate change are urgent. Efforts to reduce greenhouse gases, chemical and biologic contributors to air pollution are of critical importance. Extreme weather phenomena such as thunderstorms can trigger exacerbations of asthma attacks and need to be prevented with a correct information and therapy.
呼吸道过敏与空气污染和气候变化密切相关。由于气候变化,花粉和霉菌等过敏原的大气含量增加,导致 IgE 介导的过敏反应患者发生鼻炎和哮喘。花粉过敏常用于评估空气污染与过敏性呼吸道疾病的关系。花粉过敏原会引发免疫调节和促炎介质的释放,并加速易感性患者对呼吸过敏原的致敏。花粉季节的雷暴不仅会使成人,也会使花粉症儿童的呼吸道过敏和哮喘恶化。在这项研究中,我们集中研究了室外空气污染的触发(化学和生物)因素。
环境污染和气候变化对人类健康有害,尤其是对呼吸系统,对社会系统也有频繁影响。气候变化的特征是物理气象事件导致人为产生的二氧化碳(CO 2 )大量排放到大气中。致敏植物会产生更多的花粉作为对大气中高水平 CO 2 的反应。气候变化还会影响极端大气事件,如热浪、干旱、雷暴、洪水、气旋和飓风。这些气候事件,特别是花粉季节的雷暴,会增加花粉症患者哮喘发作的强度。
气候变化对花粉过敏的超敏反应的起始和发病机制有重要影响。气候变化导致花粉产量增加,改变了增加其变应原性的方面。通过气候变化的影响,植物的生长可能会发生改变,从而产生的新花粉发生变化,更多地影响人类健康。公众教育和采取政府措施预防环境污染和气候变化是紧迫的。努力减少温室气体、空气污染的化学和生物因素至关重要。雷暴等极端天气现象可能会引发哮喘发作加剧,需要通过正确的信息和治疗来预防。