Arciero R A, Little J S, Liebenberg S P, Parr T J
Orthopedics. 1986 Nov;9(11):1511-5. doi: 10.3928/0147-7447-19861101-07.
The effect of arthroscopic irrigating solutions on articular cartilage was determined by the use of an animal model. Rabbit knee joints were irrigated continuously for two hours with either normal saline, Ringer's lactate, or sterile water. Subsequently, the rate of incorporation of 35SO4 by articular cartilage was used to measure the effect of the irrigants on chondrocyte metabolism. In addition, the irrigated groups were compared to an unirrigated control group. There was no significant difference in 35SO4 incorporation between the groups. This suggested that none of the irrigating solutions used in this study adversely affected articular cartilage function. On the basis of these findings, it appears that normal saline, Ringer's lactate, and sterile water can be safely used as irrigating solutions during most arthroscopic procedures.
通过动物模型确定关节镜冲洗液对关节软骨的影响。用生理盐水、乳酸林格氏液或无菌水对兔膝关节连续冲洗两小时。随后，用关节软骨对35SO4的摄取率来衡量冲洗液对软骨细胞代谢的影响。此外，将冲洗组与未冲洗的对照组进行比较。各组之间35SO4摄取率无显著差异。这表明本研究中使用的任何一种冲洗液均未对关节软骨功能产生不利影响。基于这些发现，在大多数关节镜手术中，生理盐水、乳酸林格氏液和无菌水似乎都可安全地用作冲洗液。
