[马里大学临床研究中心实验室在严重急性呼吸综合征冠状病毒2（SARS-CoV-2）诊断中的贡献]
[Contribution of the University Clinical Research Center's laboratoryin the diagnosis of SARS-CoV-2 in Mali].
作者信息
Dramé H B, Diallo D, Coulibaly G, Kone M, Diallo F, Diarra H B, Coulibaly A, Camara F, Diakité M T, Dégoga B, Traoré F G, Somboro A, Dolo O, Denou L, Koné K, Coulibaly M, Togo Acg, Togo J, Somboro A M, Sanogo M, Bane S, Diallo M, Guindo I, Koné A, Tolofoudié M, Sarro Yds, Toloba Y, Dao S, Diakité M, Diarra B, Doumbia S
机构信息
Centre Universitaire de Recherche Clinique (UCRC), Université des Sciences, des Techniques, et des Technologies de Bamako (USTTB), Bamako, Mali.
Département de Laboratoire et de Recherche Biomédicale, Institut National de Santé Publique (INSP), Ministère de la Santé et des Affaires Sociales, Bamako, Mali.
出版信息
Mali Med. 2021;36(2):14-18.
INTRODUCTION
The rapid diagnostic capacities of laboratories in Mali have been an essential element in the response to COVID-19. The University Clinical Research center (UCRC) diagnosed the first cases of Mali COVID-19.
OBJECTIVE
The objective was to describe the contribution of the UCRC in the diagnosis of Covid-19 and to clinically and epidemiologically characterize the patients tested in the UCRC laboratory.
MATERIALS AND METHODS
A cross-sectional study was conducted during eight months of intense activity. The samples were sent from the National Institute of Public Health (INSP) to the UCRC.
RESULTS
The UCRC tested 12,406 contacts and suspected samples and confirmed the diagnosis in 1091 patients, or 9%. The most common symptoms were cough (48.78%), headache (34.14%), fatigue / weakness (34.14%), while (33.33%) of the patients were asymptomatic. The sample positivity rate among new cases decreased from May to September 2020, despite almost 230% of the number of samples tested.
CONCLUSION
The laboratory played a major role in the response and there may be a low transmission of the virus in the Malian community.
引言
马里各实验室的快速诊断能力是应对新冠疫情的关键要素。大学临床研究中心（UCRC）诊断出了马里首批新冠病例。
目的
旨在描述大学临床研究中心在新冠诊断中的贡献，并对在该中心实验室接受检测的患者进行临床和流行病学特征分析。
材料与方法
在八个月的高强度工作期间开展了一项横断面研究。样本由国家公共卫生研究所（INSP）送至大学临床研究中心。
结果
大学临床研究中心检测了12406份密切接触者及疑似样本，确诊1091例患者，确诊率为9%。最常见症状为咳嗽（48.78%）、头痛（34.14%）、乏力/虚弱（34.14%），而33.33%的患者无症状。尽管检测样本数量增加了近230%，但2020年5月至9月新病例的样本阳性率有所下降。
结论
该实验室在应对疫情中发挥了重要作用，且病毒在马里社区的传播率可能较低。
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