Deosthale Nitin, Khursheed Mateen, Choudhary Samir, Khadakkar Sonali Prabhakar, Nagwekar Chaitrika, More Harshawardhan, Amar Methwani Disha
Department of ENT, NKPSIMS and RC, Digdoh Hills, Nagpur, India.
Department of ENT, DMMC, Nagpur, India.
Indian J Otolaryngol Head Neck Surg. 2023 Dec;75(4):3373-3378. doi: 10.1007/s12070-023-04004-9. Epub 2023 Jun 23.
: Oral Submucous Fibrosis is a pre-cancerous, progressive condition caused by gutkha, areca nut consumption which is characterized by limited mouth opening, burning pain inoral cavity, stiffness and blanching of oral mucosa. : To study sociodemographic characters and clinical profile of Oral Submucous Fibrosis and to assess the association of duration of adverse habits with clinical staging of Oral Submucous Fibrosis. : This cross-sectional study of 70 clinically diagnosed cases of oral submucous fibrosis was carried out at the Tertiary Health Care Centre in Central India. Over the course of two years, demographic and clinical information, including specifics on addiction and its duration, was gathered. On the basis of symptoms, the presence of palpable fibrous bands, and measuring mouth opening, clinical staging was carried out. : The average age of the patients in the study was 33.2 ± 12.66 years with Male female ratio of 3:1. Significantly higher proportion of patients belonged to low socioeconomic status. The maximum number of patients were seen in stage III (62.86%) followed by Stage II (21.43%) and subjects who had the adverse habits for a period of 5 to 10 years had more severe OSMF. : In the present study, frequency of OSMF was more in young age group and in males. There was higher frequency of disease in lower socioeconomic status. Longer duration addiction was highly associated with severity of clinical stage of OSMF.
口腔黏膜下纤维化是一种癌前的、进行性疾病,由咀嚼槟榔引起,其特征为张口受限、口腔灼痛、口腔黏膜僵硬及变白。
研究口腔黏膜下纤维化的社会人口学特征和临床概况,并评估不良习惯持续时间与口腔黏膜下纤维化临床分期的相关性。
在印度中部的三级医疗保健中心对70例临床诊断为口腔黏膜下纤维化的病例进行了这项横断面研究。在两年的时间里,收集了人口统计学和临床信息,包括成瘾情况及其持续时间的具体信息。根据症状、可触及的纤维条索的存在情况以及测量张口度进行临床分期。
研究中患者的平均年龄为33.2±12.66岁,男女比例为3:1。属于社会经济地位较低的患者比例显著更高。III期患者数量最多(62.86%),其次是II期(21.43%),有5至10年不良习惯的患者口腔黏膜下纤维化更严重。
在本研究中,口腔黏膜下纤维化在年轻年龄组和男性中更为常见。社会经济地位较低的人群中疾病发生率更高。成瘾持续时间越长与口腔黏膜下纤维化临床分期的严重程度高度相关。