超声“宫颈征”：胆囊颈部恶性肿瘤的一种新辅助征象。
Sonographic "Cervix Sign": A New Ancillary Sign of Gallbladder Neck Malignancy.
作者信息
Rana Pratyaksha, Pruthi Himanshu, Gupta Pankaj, Chhabra Manika, Soundararajan Raghuraman, Singh Shravya, Gulati Ajay, Das Chandan K, Yadav Thakur D, Gupta Vikas, Gupta Parikshaa, Saikia Uma N, Dutta Usha, Sandhu Manavjit
机构信息
Department of Radiodiagnosis and Imaging, Nehru Hospital, Postgraduate Institute of Medical Education and Research, Ground Floor, Sector 12, Chandigarh, 160012, India.
Department of Clinical Hematology and Medical Oncology, Nehru Hospital, Postgraduate Institute of Medical Education and Research, 4th Floor, Sector 12, Chandigarh, 160012, India.
出版信息
J Clin Exp Hepatol. 2023 Nov-Dec;13(6):972-976. doi: 10.1016/j.jceh.2023.05.013. Epub 2023 May 30.
BACKGROUND
The differentiation of benign and malignant gallbladder wall thickening is challenging. The purpose of this study is to evaluate a new sonographic sign, "cervix sign" for differentiation of benign and malignant gallbladder neck thickening.
METHODS
This retrospective study comprised consecutive patients with gallbladder neck thickening who underwent sonography between August 2019 and December 2021. The presence of "cervix sign" was assessed by two radiologists independently.
RESULTS
Sixty-five patients had gallbladder neck thickening (28 malignant and 37 benign). The sonographic "cervix sign" was present in 18 (64%) patients with malignant thickening and in only one (2.7%) patient with benign thickening ( = 0.0001). The mean wall thickness was greater, and symmetric wall thickening and liver metastases were more common in malignant thickening with "cervix sign" (without reaching statistical significance). There was substantial agreement (kappa = 0.78) between the two observers for the cervix sign.
CONCLUSION
Sonographic "cervix sign" is a useful ancillary feature of gallbladder neck cancer.
背景
鉴别胆囊壁增厚的良恶性具有挑战性。本研究旨在评估一种新的超声征象——“宫颈征”，以鉴别胆囊颈部增厚的良恶性。
方法
这项回顾性研究纳入了2019年8月至2021年12月期间接受超声检查的连续性胆囊颈部增厚患者。由两名放射科医生独立评估“宫颈征”的存在情况。
结果
65例患者存在胆囊颈部增厚（28例为恶性，37例为良性）。超声“宫颈征”在18例（64%）恶性增厚患者中出现，而在仅1例（2.7%）良性增厚患者中出现（P = 0.0001）。在有“宫颈征”的恶性增厚中，平均壁厚度更大，壁增厚对称和肝转移更常见（未达到统计学意义）。两位观察者对宫颈征的评估有高度一致性（kappa = 0.78）。
结论
超声“宫颈征”是胆囊颈部癌的一个有用的辅助特征。
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