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经皮内镜经椎间孔入路与经皮内镜关节突间入路治疗腰椎减压术后邻近节段疾病的比较:一项临床回顾性研究。

Comparison of Percutaneous Endoscopic Transforaminal and Interlaminar Approaches in Treating Adjacent Segment Disease Following Lumbar Decompression Surgery: A Clinical Retrospective Study.

机构信息

Department of Spine Surgery, The Affiliated Hospital of Qingdao University, Shandong Province, People's Republic of China.

Department of Orthopedics, People's Hospital of Rizhao Lanshan, Shandong Province, People's Republic of China.

出版信息

Pain Physician. 2023 Nov;26(7):E833-E842.

PMID:37976490
Abstract

BACKGROUND

Adjacent segment disease (ASD) is a common complication following posterior disc decompression and fusion surgery. Percutaneous endoscopic lumbar decompression surgery (PELD) has been used to treat ASD through either a transforaminal or interlaminar approach. However, to our limited knowledge there are no reports comparing the 2 approaches for treating ASD.

OBJECTIVE

To evaluate clinical outcomes of PELD in treating ASD and comparing the surgical results and complications between the 2 approaches. This may be helpful for spinal surgeons when decision-making ASD treatment.

STUDY DESIGN

A clinical retrospective study.

SETTING

This study was conducted at the Department of Orthopedics of the Affiliated Hospital of Qingdao University.

METHODS

From January 2015 through December 2019, a total of 68 patients with ASD who underwent PELD after lumbar posterior decompression with fusion surgery were included in this study. The patients were divided into a percutaneous endoscopic transforaminal decompression (PETD) group and a percutaneous endoscopic interlaminar decompression (PEID) group according to the approach used. The demographic characteristics, radiographic and clinical outcomes, and complications were recorded in both groups through a chart review.

RESULTS

Of the 68 patients, 40 underwent PEID and 28 patients underwent PETD. Compared with their preoperative Visual Analog Scale (VAS) pain score and Oswestry Disability Index (ODI) score, all patients had significant postoperative improvement at 3 months, 6 months, one year and at the latest follow-up. There were no significant statistical differences in the VAS and ODI scores between PETD and PEID groups with a P value > 0.05. There was a significant statistical difference in the average fluoroscopy times between the PETD and PEID groups with a P value = 0.000. Revision surgery occurred in 8 patients: 6 patients who underwent PETD and 2 patients who underwent PEID. The revision rate showed a significant statistical difference between the 2 approaches with a P value = 0.039.

LIMITATIONS

Firstly, the number of patients included in this study was small. More patients are needed in a further study. Secondly, the follow-up time was limited in this study. There is still no conclusion about whether the primary decompression with instruments will increase the reoperation rate after a PELD, and a longer follow-up is needed in the future. Thirdly, this study was a clinical retrospective study. Randomized or controlled trials are needed in the future in order to achieve a higher level of evidence. Fourthly, there were debates about PELD approach choices for ASDs, which may affect the comparison results between PETD and PEID. In our study, the approaches were mainly determined by the level and types of disc herniation, and the surgeons' preference. More patients with an ASD with different levels and types of disc herniation and surgical approaches are needed in the future to eliminate these biases.

CONCLUSION

Percutaneous endoscopic lumbar decompression surgery is a feasible option for ASD following lumbar decompression surgery with instruments. Compared with PETD, PEID seems to be a better approach to treat symptomatic ASDs.

摘要

背景

相邻节段疾病(ASD)是后路椎间盘减压融合术后常见的并发症。经皮内镜腰椎减压术(PELD)已被用于通过经椎间孔或经椎间孔入路治疗 ASD。然而,据我们所知,尚无比较这两种方法治疗 ASD 的报道。

目的

评估 PELD 治疗 ASD 的临床效果,并比较两种方法的手术结果和并发症。这可能有助于脊柱外科医生在决定 ASD 治疗方案时做出决策。

研究设计

临床回顾性研究。

地点

本研究在青岛大学附属医院骨科进行。

方法

2015 年 1 月至 2019 年 12 月,共有 68 例后路减压融合术后 ASD 患者接受 PELD 治疗,纳入本研究。根据采用的方法,患者分为经皮内镜经椎间孔减压(PETD)组和经皮内镜经椎间孔入路减压(PEID)组。通过病历回顾记录两组患者的一般资料、影像学和临床结果及并发症。

结果

68 例患者中,40 例行 PEID,28 例行 PETD。与术前视觉模拟评分(VAS)疼痛评分和 Oswestry 功能障碍指数(ODI)评分相比,所有患者术后 3 个月、6 个月、1 年和末次随访时均有明显改善,VAS 和 ODI 评分在 PETD 组和 PEID 组之间无统计学差异(P>0.05)。PETD 组和 PEID 组平均透视时间有统计学差异(P=0.000)。8 例患者行翻修手术:6 例行 PETD,2 例行 PEID。两种方法的翻修率有统计学差异(P=0.039)。

局限性

首先,本研究纳入的患者数量较少,需要更多的患者进行进一步研究。其次,本研究的随访时间有限,关于后路减压融合术后初次减压内固定是否会增加 PELD 后的再手术率尚无定论,需要更长时间的随访。第三,本研究为临床回顾性研究,未来需要随机对照试验以达到更高的证据水平。第四,对于 ASD 的 PELD 入路选择存在争议,这可能会影响 PETD 和 PEID 之间的比较结果。在本研究中,入路主要取决于椎间盘突出的水平和类型以及术者的偏好。未来需要更多不同水平和类型的椎间盘突出症及手术入路的 ASD 患者,以消除这些偏倚。

结论

经皮内镜腰椎减压术是后路减压融合术后治疗 ASD 的一种可行方法。与 PETD 相比,PEID 似乎是治疗有症状 ASD 的更好方法。

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