美国心脏协会的新“生命必备 8 项”评分与心血管疾病相关：一项全国性的横断面分析。
American Heart Association's new 'Life's Essential 8' score in association with cardiovascular disease: a national cross-sectional analysis.
机构信息
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning Province, PR China.
Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, No.1163 Xinmin Street, Changchun, Jilin, 130021, China.
出版信息
Public Health. 2023 Dec;225:336-342. doi: 10.1016/j.puhe.2023.10.027. Epub 2023 Nov 16.
OBJECTIVE
The American Heart Association (AHA) has recently updated and enhanced the quantification of cardiovascular health by using the Life's Essential 8 (LE8) score. We intended to examine the correlation between cardiovascular health status, as measured by the new LE8 score, and cardiovascular disease (CVD) in US adults.
STUDY DESIGN
National cross-sectional study.
METHODS
A total of 24,730 individuals without pregnancy and with complete data from 2007 to 2018 enrolled in the study. The overall LE8 score was divided into low, moderate, and high groups. Multivariate logistic regressions were used to assess the odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between the LE8 score and the presence of CVD.
RESULTS
Overall, the high LE8 group had a younger age (20-59 years, 82.95%) and more females (60.09%) compared to the low LE8 group. Moderate and high LE8 correlated negatively with the presence of CVD (moderate, OR: 0.46, 95% CI: 0.39-0.54; high, OR: 0.26, 95% CI: 0.21-0.33). One standard deviation increment in the LE8 score correlated significantly with lower odds of CVD (OR: 0.64; 95% CI: 0.60-0.69). Further stratification analysis also detected a significant relationship between the new LE8 score and CVD, and the result was enhanced among the young and women (P-interaction<0.001).
CONCLUSIONS
Higher LE8 score correlated with lower odds of CVD, especially among the young and women.
目的
美国心脏协会（AHA）最近通过使用“生命的八项基本要素（LE8）”评分更新并增强了心血管健康的量化评估。我们旨在研究新的 LE8 评分所衡量的心血管健康状况与美国成年人心血管疾病（CVD）之间的相关性。
研究设计
全国性横断面研究。
方法
共有 24730 名无妊娠且 2007 年至 2018 年期间数据完整的个体纳入研究。将总体 LE8 评分分为低、中、高组。采用多变量逻辑回归评估 LE8 评分与 CVD 存在之间的比值比（OR）和 95%置信区间（CI）。
结果
总体而言，与低 LE8 组相比，高 LE8 组年龄更轻（20-59 岁，82.95%），女性比例更高（60.09%）。中、高 LE8 与 CVD 呈负相关（中，OR：0.46，95%CI：0.39-0.54；高，OR：0.26，95%CI：0.21-0.33）。LE8 评分每增加一个标准差，CVD 的几率显著降低（OR：0.64；95%CI：0.60-0.69）。进一步的分层分析还发现，新的 LE8 评分与 CVD 之间存在显著关系，且在年轻人和女性中更为明显（P 交互作用<0.001）。
结论
较高的 LE8 评分与 CVD 的几率降低相关，尤其是在年轻人和女性中。
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