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20 年随访时内侧胶原半月板植入物(CMI)丧失软骨保护作用。

Loss of chondroprotection of medial collagen meniscus implant (CMI) at 20-year follow-up.

机构信息

II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, 40136, Italy; Dipartimento di Scienze Biomediche e Neuromotorie DIBINEM, Università di Bologna, Bologna, 40126, Italy.

II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, 40136, Italy.

出版信息

J ISAKOS. 2024 Apr;9(2):116-121. doi: 10.1016/j.jisako.2023.11.004. Epub 2023 Nov 17.

Abstract

OBJECTIVE

The mid-term results of the collagen meniscus implant (CMI) procedure for the replacement of partial meniscus defects have already been described. However, there is a paucity of long-term comparative studies. This study aimed to compare the clinical outcomes, failures, and osteoarthritis progression of patients who underwent partial medial meniscectomy and medial CMI implantation.

METHODS

Thirty-six nonconsecutive patients with medial meniscus injuries that underwent medial CMI (MCMI) implantation or partial medial meniscectomy (PMM) between 1997 and 2000 were included in a prospective study with an intermediate 10-year follow-up examination and a final follow-up examination at 20-year follow-up. Outcome measures at the 20-year follow-up included the Lysholm score, visual analogue scale (VAS) for pain, International Knee Documentation Committee (IKDC) knee form , and Tegner activity level. Bilateral weight-bearing radiographs were also performed to evaluate hip-knee-angle (HKA) and the medial joint line height (JL). Data regarding complications and failures were also collected.

RESULTS

At the 20-year follow-up, 31 patients (83% follow-up rate) with a mean age of 60.7 ​± ​8.9 years were included in the final analysis (21.1 ​± ​1.2 years follow-up). Four reoperations and one failure per group were reported. When comparing the clinical results of the two groups, no difference was found considering the Lysholm score, Knee Injury and Osteoarthritis Outcome Score (KOOS), Tegner, and the IKDC. Moreover, 20 patients underwent radiographic examination (10 MCMI, 10 ​MM), and no statistically significant difference was reported concerning the JL, HKA, and the presence and incidence of osteoarthritis between the two groups.

CONCLUSION

The CMI implant for partial medial meniscectomy provided good long-term results and a low failure rate. However, differently from the 10 years follow-up, the clinical and the radiological outcomes were not superior compared to the medial meniscectomy group. The present study's result suggests that using a medial scaffold is not chondroprotective.

LEVEL OF EVIDENCE

III, Prospective case-control study.

摘要

目的

已经描述了胶原蛋白半月板植入物(CMI)手术治疗部分半月板缺损的中期结果。然而,长期比较研究很少。本研究旨在比较行内侧半月板部分切除术和内侧 CMI 植入术的患者的临床结果、失败率和骨关节炎进展情况。

方法

1997 年至 2000 年间,对 36 例内侧半月板损伤患者进行前瞻性研究,其中 18 例行内侧 CMI(MCMI)植入术,18 例行内侧半月板部分切除术(PMM)。10 年中期随访检查和 20 年最终随访检查。20 年随访时的评估指标包括 Lysholm 评分、疼痛视觉模拟评分(VAS)、国际膝关节文献委员会(IKDC)膝关节评分、Tegner 活动水平。还进行双侧负重位 X 线检查以评估髋膝角(HKA)和内侧关节线高度(JL)。收集并发症和失败的数据。

结果

20 年随访时,31 例患者(83%随访率)纳入最终分析,平均年龄为 60.7±8.9 岁(10.2±1.2 年随访)。每组报告了 4 例再手术和 1 例失败。比较两组的临床结果,Lysholm 评分、膝关节损伤和骨关节炎结果评分(KOOS)、Tegner 和 IKDC 评分均无差异。此外,20 例患者进行了影像学检查(10 例 MCMI,10 例 PMM),两组间 JL、HKA、骨关节炎的存在和发生率无统计学差异。

结论

CMI 植入物治疗部分内侧半月板切除术提供了良好的长期结果和低失败率。然而,与 10 年随访不同,与内侧半月板切除术组相比,临床和影像学结果并不优越。本研究结果表明,使用内侧支架并不能起到保护软骨的作用。

证据等级

III,前瞻性病例对照研究。

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