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灌注指数作为一种非侵入性的监测再灌注和再植手指的方法。

The perfusion index as a noninvasive method for monitoring revascularized and replanted digits.

机构信息

Department of Trauma Surgery, Orthopedics, Plastic and Hand Surgery, University of Augsburg, Augsburg, Germany.

Department of Plastic, Hand and Reconstructive Surgery, University of Regensburg, Regensburg, Germany.

出版信息

Clin Hemorheol Microcirc. 2024;86(1-2):143-152. doi: 10.3233/CH-238120.

Abstract

BACKGROUND

Monitoring replanted digits remains a challenging task in microsurgical units. Previous studies have indicated the perfusion index (PI), a parameter directly proportional to the blood flow, might be a useful tool.

OBJECTIVE

The PI is evaluated as a monitoring tool in patients with replanted digits.

METHODS

This prospective, non-interventional study includes 31 patients with revascularized or replanted digits. After successful revascularization or replantation, the PI and peripheral oxygen saturation of the affected finger and its contralateral equivalent were measured simultaneously. The values were detected by the device Radical-97® Pulse CO-Oximeter® (Masimo Corporation, 52 Discovery, Irvine, CA 92618, USA).

RESULTS

The median PI of affected fingers was 3.5±0.56 for revascularized and 2.2±0.8 for replanted fingers. The difference between the PI values of replanted digits and the healthy contralateral side was highly significant (p < 0.0001). The area under the curve in the receiver operating characteristics was 0.92 for a PI difference > 80.49% and predicted a loss of replant with a specificity of 100% and a sensitivity of 75%.

CONCLUSION

The assessment of the PI in patients with reperfusion of a vascular compromised digit is a useful tool to continuously monitor peripheral perfusion. The dynamic behavior of the PI is essential to detect perfusion disturbance.

摘要

背景

监测再植手指仍然是显微外科的一项挑战。先前的研究表明,灌注指数(PI)与血流直接成正比,可能是一种有用的工具。

目的

评估 PI 作为再植手指的监测工具。

方法

这是一项前瞻性、非干预性研究,共纳入 31 例再血管化或再植的患者。成功再血管化或再植后,同时测量患指及其对侧相应指的 PI 和外周血氧饱和度。使用 Radical-97® Pulse CO-Oximeter®(Masimo 公司,52 Discovery,Irvine,CA 92618,美国)检测数值。

结果

再灌注手指的 PI 中位数为 3.5±0.56,再植手指的 PI 中位数为 2.2±0.8。再植手指与健康对侧手指的 PI 值差异具有统计学意义(p<0.0001)。PI 差值>80.49%的受试者工作特征曲线下面积为 0.92,PI 差值预测再植丢失的特异性为 100%,敏感性为 75%。

结论

评估血管受损手指再灌注患者的 PI 是监测外周灌注的有用工具。PI 的动态行为对于检测灌注障碍至关重要。

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