Division of Neonatology, Department of Pediatrics UCLA Mattel Children's Hospital Los Angeles CA USA.
Diagnostic Cardiovascular Imaging Laboratory, Department of Radiological Sciences David Geffen School of Medicine, UCLA Los Angeles CA USA.
J Am Heart Assoc. 2023 Nov 21;12(22):e030640. doi: 10.1161/JAHA.123.030640. Epub 2023 Nov 20.
Standard of care echocardiography can have limited diagnostic accuracy in certain cases of fetal congenital heart disease. Prenatal cardiovascular magnetic resonance (CMR) imaging has potential to provide additional anatomic imaging information, including excellent soft tissue images in multiple planes, improving prenatal diagnostics and in utero hemodynamic assessment. We conducted a literature review of fetal CMR, including its development and implementation into clinical practice, and compiled and analyzed the results. Our findings included the fact that technological and innovative approaches are required to overcome some of the challenges in fetal CMR, in part due to the dynamic nature of the fetal heart. A number of reconstruction algorithms and cardiac gating strategies have been developed over time to improve fetal CMR image quality, allowing unique investigations into fetal hemodynamics, oxygenation, and growth. Studies demonstrate that incorporating CMR in the prenatal arena influences postnatal clinical management. With further refinement and experience, fetal CMR in congenital heart disease continues to evolve and demonstrate ongoing potential as a complementary imaging modality to fetal echocardiography in the care of these patients.
标准的超声心动图检查在某些胎儿先天性心脏病的情况下可能具有有限的诊断准确性。产前心血管磁共振(CMR)成像有可能提供额外的解剖成像信息,包括多个平面上的出色软组织图像,从而改善产前诊断和宫内血液动力学评估。我们对胎儿 CMR 进行了文献回顾,包括其发展和在临床实践中的应用,并对结果进行了汇编和分析。我们的研究结果表明,需要采用技术和创新方法来克服胎儿 CMR 中的一些挑战,部分原因是胎儿心脏的动态特性。随着时间的推移,已经开发出许多重建算法和心脏门控策略来提高胎儿 CMR 图像质量,从而可以对胎儿血液动力学、氧合和生长进行独特的研究。研究表明,在产前领域中引入 CMR 会影响产后的临床管理。随着进一步的改进和经验积累,先天性心脏病中的胎儿 CMR 不断发展,并继续作为胎儿超声心动图的补充成像方式,为这些患者的治疗提供潜在的作用。