Mazón-Ortiz Gabriel, Cerda-Mejía Galo, Gutiérrez Morales Eberto, Diéguez-Santana Karel, Ruso Juan M, González-Díaz Humberto
Facultad Ciencias de la Vida, Facultad Ciencias de la Tierra y Agua, Universidad Regional Amazónica Ikiam, Parroquia Muyuna km 7 vía Alto Tena, Tena 150150, Napo, Ecuador.
Soft Matter and Molecular Biophysics Group, Department of Applied Physics and Institute of Materials (iMATUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Diseases. 2023 Oct 28;11(4):153. doi: 10.3390/diseases11040153.
Leishmaniasis is a neglected tropical illness with a wide variety of clinical signs ranging from visceral to cutaneous symptoms, resulting in millions of new cases and thousands of fatalities reported annually. This article provides a bibliometric analysis of the main authors' contributions, institutions, and nations in terms of productivity, citations, and bibliographic linkages to the application of nanoparticles (NPs) for the treatment of leishmania. The study is based on a sample of 524 Scopus documents from 1991 to 2022. Utilising the Bibliometrix R-Tool version 4.0 and VOSviewer software, version 1.6.17 the analysis was developed. We identified crucial subjects associated with the application of NPs in the field of antileishmanial development (NPs and drug formulation for leishmaniasis treatment, animal models, and experiments). We selected research topics that were out of date and oversaturated. Simultaneously, we proposed developing subjects based on multiple analyses of the corpus of published scientific literature (title, abstract, and keywords). Finally, the technique used contributed to the development of a broader and more specific "big picture" of nanomedicine research in antileishmanial studies for future projects.
利什曼病是一种被忽视的热带疾病，具有从内脏症状到皮肤症状的多种临床体征，每年报告数百万新病例和数千人死亡。本文对纳米颗粒（NPs）用于治疗利什曼原虫的主要作者贡献、机构和国家进行了文献计量分析，涉及生产力、引文以及文献联系。该研究基于1991年至2022年的524篇Scopus文献样本。利用Bibliometrix R-Tool 4.0版本和VOSviewer 1.6.17版本软件进行了分析。我们确定了与纳米颗粒在抗利什曼原虫发展领域应用相关的关键主题（用于利什曼病治疗的纳米颗粒和药物制剂、动物模型及实验）。我们挑选了过时和过度饱和的研究主题。同时，我们基于对已发表科学文献语料库（标题、摘要和关键词）的多重分析提出了新兴主题。最后，所使用的技术有助于为未来项目在抗利什曼原虫研究中纳米医学研究构建更广泛、更具体的“全景”。
