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阴茎鳞状细胞癌中,与经典视频内镜腹股沟淋巴结清扫术相比,更倾向于采用侧方视频内镜腹股沟淋巴结清扫术:来自单中心21例患者的经验教训

Preferring Lateral Video Endoscopic Inguinal Lymph Node Dissection Over Classic Video Endoscopic Inguinal Lymph Node Dissection in Squamous Cell Carcinoma of Penis: Lessons Learnt from Twenty-One Patients at a Single Center.

作者信息

Yadav Pradhuman, Sharma Amit, Biswal Deepak Kumar, Rt Raghavendra

机构信息

Department of Urology, All India Institute of Medical Sciences, Raipur, India.

出版信息

Urol Res Pract. 2023 Nov;49(6):370-375. doi: 10.5152/tud.2023.23097.

DOI:10.5152/tud.2023.23097
PMID:37987306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10765180/
Abstract

OBJECTIVE

Inguinal lymphadenectomy is essential for staging and disease control. Minimally invasive techniques are recently replacing open techniques to reduce complications. We present our experience and lessons learnt from 21 patients who underwent lateral video endoscopic inguinal lymphadenectomy (L-VEIL) for penile malignancy.

METHODS

All patients above 18 years of age with histopathology-confirmed squamous cell carcinoma penis with stages ≥ T1b and T1a with persistent lymphadenopathy who underwent L-VEIL over a period of 2 years (2020-2022) were included. The data were analyzed on the basis of intraoperative and postoperative complications, lymph node yield, hospital stay, and histopathology report.

RESULTS

Forty-one lower limbs of 21 patients underwent L-VEIL during the abovementioned period. Median age was 52 years. Mean operative time (on 1 side) was 80 minutes. Median lymph node yield per side was 7.2. Intraoperatively, 1 patient had a vascular injury at the saphenofemoral junction, requiring conversion to open. Postoperative complications were superficial surgical site infection (n=4), lymphedema (n=1), and lymphocoele (n=3), one of which was drained by pigtail catheter. One patient required exploration on the second postoperative day because of vascular injury. Average duration of hospital stay was 3 days. The median time of drain removal was 13 days. Histopathology suggested seminoma in 1 patient and mature teratoma in 1 patient; the rest of the patients' reports were negative for malignancy.

CONCLUSION

The L-VEIL is safe and feasible, and there is a reduction (~30%) in complications; oncological outcomes are also not affected. It has better ergonomics, resulting in ease and comfort for surgeons when compared with classical VEIL.

摘要

目的

腹股沟淋巴结清扫术对于分期和疾病控制至关重要。近年来,微创技术正逐渐取代开放手术以减少并发症。我们介绍了21例因阴茎恶性肿瘤接受侧方视频内镜腹股沟淋巴结清扫术(L-VEIL)患者的经验及教训。

方法

纳入所有年龄在18岁以上、经组织病理学确诊为阴茎鳞状细胞癌、分期≥T1b且T1a伴有持续性淋巴结病、在2年期间(2020 - 2022年)接受L-VEIL手术的患者。根据术中及术后并发症、淋巴结收获量、住院时间和组织病理学报告对数据进行分析。

结果

在上述期间,21例患者的41条下肢接受了L-VEIL手术。中位年龄为52岁。平均手术时间(单侧)为80分钟。每侧中位淋巴结收获量为7.2个。术中,1例患者在大隐静脉股静脉交界处发生血管损伤,需转为开放手术。术后并发症包括浅表手术部位感染(n = 4)、淋巴水肿(n = 1)和淋巴囊肿(n = 3),其中1例通过猪尾导管引流。1例患者术后第二天因血管损伤需要探查。平均住院时间为3天。引流管拔除的中位时间为13天。组织病理学提示1例患者为精原细胞瘤,1例患者为成熟畸胎瘤;其余患者报告无恶性肿瘤。

结论

L-VEIL安全可行,并发症减少(约30%);肿瘤学结局也未受影响。与传统VEIL相比,它具有更好的人体工程学设计,使外科医生操作更轻松舒适。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/bde575020f18/urp-49-6-370_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/9d20d4761b4e/urp-49-6-370_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/1b03b9cf54f0/urp-49-6-370_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/07fd7fd09aee/urp-49-6-370_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/5b7f7335548b/urp-49-6-370_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/bde575020f18/urp-49-6-370_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/9d20d4761b4e/urp-49-6-370_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/1b03b9cf54f0/urp-49-6-370_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/07fd7fd09aee/urp-49-6-370_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/5b7f7335548b/urp-49-6-370_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212d/10765180/bde575020f18/urp-49-6-370_f005.jpg

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Prospective study comparing video-endoscopic radical inguinal lymph node dissection (VEILND) with open radical ILND (OILND) for penile cancer over an 8-year period.一项前瞻性研究,在8年时间里比较视频内镜下根治性腹股沟淋巴结清扫术(VEILND)与开放性根治性腹股沟淋巴结清扫术(OILND)治疗阴茎癌的效果。
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