Perovnik Matej, Pretnar Oblak Janja, Frol Senta
Department of Vascular Neurology, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.
Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Neurol Int. 2023 Nov 2;15(4):1352-1358. doi: 10.3390/neurolint15040085.
Here, we present a case series of four patients diagnosed with acute ischaemic stroke due to occlusion of the artery of Percheron (AOP), a rare stroke variant, observed in a single emergency centre within a three-month period. AOP occlusion is characterized by bilateral thalamic infarction with or without involvement of the mesencephalon. The presenting symptoms are diverse and not specific, but commonly include disturbance of consciousness, memory impairment, and vertical gaze palsy. In addition, due to the location of the infarction, imaging recognition is challenging and AOP occlusion often remains undiagnosed. This paper emphasizes the necessity of early recognition and appropriate management of AOP occlusion to significantly impact patient outcomes. Moreover, we argue that the condition might be more common than previously thought and that misdiagnosis or delay in diagnosis may lead to inappropriate treatment and potential failure to apply thrombolysis within the required timeframe.
在此，我们呈现了一个病例系列，涉及4名被诊断为因大脑后动脉丘脑穿通动脉（AOP）闭塞导致急性缺血性卒中的患者，这是一种罕见的卒中变体，在一个急诊中心三个月内观察到。AOP闭塞的特征是双侧丘脑梗死，可伴有或不伴有中脑受累。其临床表现多样且不具特异性，但通常包括意识障碍、记忆障碍和垂直凝视麻痹。此外，由于梗死的位置，影像学识别具有挑战性，AOP闭塞常常未被诊断出来。本文强调早期识别和适当处理AOP闭塞对于显著影响患者预后的必要性。此外，我们认为这种情况可能比以前认为的更常见，误诊或诊断延迟可能导致不适当的治疗，并可能无法在规定时间内进行溶栓治疗。
