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改善长新冠的分类学:并非易事。

Improving the nosology of Long COVID: it is not so simple.

机构信息

Rheumatology/Immunology, Cleveland Clinic, Cleveland, Ohio, USA

Rheumatology Research, Swedish Medical Center, Seattle, Washington, USA.

出版信息

Ann Rheum Dis. 2024 Jan 2;83(1):9-11. doi: 10.1136/ard-2023-224844.

Abstract

Long COVID is a diagnostic label currently given to those suffering from a poorly understood state of incomplete recovery or who have development of a myriad of medically unexplained symptoms occurring in the wake of infection with SARS CoV-2 that is both poorly understood and controversial. Many of the features of one of the most common clinical endotypes of Long COVID are shared by a condition well familiar to all rheumatologists and one with a large body of epidemiologic, clinical and basic research accrued over many decades namely the syndrome of fibromyalgia. Some have recently suggested that Long COVID may merely be a new name for fibromyalgia and that this diagnosis is indeed the condition that many or most may be suffering from as a post infectious sequela. In this Viewpoint we argue that while the parallels between the clinical syndrome experienced by many of those currently labeled as Long COVID and fibromyalgia are strong we should be not too quick to rename the disorder. We further argue that relabeling Long COVID as fibromyalgia is clinically reductionistic and any such relabeling may be attended by harm in both the design and execution of a future research agenda as well to patients who may be inadvertently and unfortunately pejoritised by such labeling. We further explore the parallels and differences between Long COVID and fibromyalgia and outline areas of needed future research and care.

摘要

长新冠是一个诊断标签,目前用于描述那些患有不明原因的不完全康复状态或在感染 SARS-CoV-2 后出现大量医学无法解释的症状的人群,这种状态既未被充分理解,也存在争议。长新冠的一个最常见临床表型的许多特征与所有风湿病学家都非常熟悉的一种疾病相似,这种疾病具有大量经过数十年积累的流行病学、临床和基础研究。最近有人提出,长新冠可能只是纤维肌痛的一个新名称,而且这种诊断确实是许多人或大多数人可能患有作为感染后后遗症的疾病。在这篇观点文章中,我们认为,虽然目前被标记为长新冠的许多人的临床综合征与纤维肌痛之间存在很强的相似性,但我们不应急于重新命名该疾病。我们进一步认为,将长新冠重新命名为纤维肌痛在临床上是简化主义的,任何这种重新命名都可能会对未来的研究计划的设计和执行以及对可能因这种标签而不幸受到不利影响的患者造成伤害。我们进一步探讨了长新冠和纤维肌痛之间的相似之处和差异,并概述了未来需要研究和关注的领域。

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