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择期全髋关节和全膝关节置换术对老年骨科患者身体机能的影响:一项前瞻性干预研究。

The impact of elective total hip and knee arthroplasty on physical performance in orthogeriatric patients: a prospective intervention study.

机构信息

Department of Orthopaedic Surgery, Regensburg University Medical Center, Bad Abbach, Germany.

Department of Health Economics, Technical University of Munich, Munich, Germany.

出版信息

BMC Geriatr. 2023 Nov 21;23(1):763. doi: 10.1186/s12877-023-04460-6.

DOI:10.1186/s12877-023-04460-6
PMID:37990164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10664286/
Abstract

BACKGROUND

Osteoarthritis is a prevalent condition in older adults that leads to reduced physical function in many patients and ultimately requires hip or knee replacement. The aim of the study was to determine the impact of hip and knee arthroplasty on the physical performance of orthogeriatric patients with osteoarthritis.

METHODS

In this prospective study, we used data from 135 participants of the ongoing Special Orthopaedic Geriatrics (SOG) trial, funded by the German Federal Joint Committee (GBA). Physical function, measured by the Short Physical Performance Battery (SPPB), was assessed preoperatively, 3 and 7 days postoperatively, 4-6 weeks and 3 months after hip and knee arthroplasty. For the statistical analysis, the Friedman test and post-hoc tests were used.

RESULTS

Of the 135 participants with a mean age of 78.5 ± 4.6 years, 81 underwent total hip arthroplasty and 54 total knee arthroplasty. In the total population, SPPB improved by a median of 2 points 3 months after joint replacement (p < 0.001). In the hip replacement group, SPPB increased by a median of 2 points 3 months after surgery (p < 0.001). At 3 months postoperatively, the SPPB increased by a median of 1 point in the knee replacement group (p = 0.003).

CONCLUSION

Elective total hip and knee arthroplasty leads to a clinically meaningful improvement in physical performance in orthogeriatric patients with osteoarthritis after only a few weeks.

TRIAL REGISTRATION

This study is part of the Special Orthopaedic Geriatrics (SOG) trial, German Clinical Trials Register DRKS00024102. Registered on 19 January 2021.

摘要

背景

骨关节炎是老年人中常见的疾病,许多患者因此身体机能下降,最终需要髋关节或膝关节置换。本研究旨在确定髋关节和膝关节置换对患有骨关节炎的老年骨科患者身体机能的影响。

方法

本前瞻性研究使用了德国联邦联合委员会(GBA)资助的正在进行的特殊骨科老年病学(SOG)试验的 135 名参与者的数据。使用短体物理表现电池(SPPB)测量身体机能,在髋关节和膝关节置换术前、术后 3 天和 7 天、4-6 周和 3 个月进行评估。统计分析采用 Friedman 检验和事后检验。

结果

在 135 名平均年龄为 78.5±4.6 岁的参与者中,81 名接受了全髋关节置换术,54 名接受了全膝关节置换术。在总人群中,关节置换术后 3 个月 SPPB 中位数提高了 2 分(p<0.001)。在髋关节置换组中,手术后 3 个月 SPPB 中位数增加了 2 分(p<0.001)。在膝关节置换组中,术后 3 个月 SPPB 中位数增加了 1 分(p=0.003)。

结论

在患有骨关节炎的老年骨科患者中,选择性全髋关节和膝关节置换术后仅数周即可显著改善身体机能。

试验注册

本研究是特殊骨科老年病学(SOG)试验的一部分,德国临床试验注册处 DRKS00024102。注册于 2021 年 1 月 19 日。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/10664286/1704099669cb/12877_2023_4460_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/10664286/851395fda6b4/12877_2023_4460_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/10664286/1704099669cb/12877_2023_4460_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/10664286/851395fda6b4/12877_2023_4460_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/10664286/1704099669cb/12877_2023_4460_Fig2_HTML.jpg

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