Hany Mohamed, Torensma Bart
Department of Surgery, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Clinical Epidemiologist, Leiden University Medical Center (LUMC), Leiden, the Netherlands.
Obes Pillars. 2022 May 6;2:100019. doi: 10.1016/j.obpill.2022.100019. eCollection 2022 Jun.
This study aimed to describe the incidence and clinical presentation of fully vaccinated and unvaccinated patients who tested positive for COVID-19 in the first year after Madina Women's Hospital in Alexandria, Egypt, resumed bariatric surgery procedures. (The clinic was closed between March 2020 and reopened in mid-October 2020).
This prospective cohort study was conducted between November 2020 till the end of December 2021. We identified patients undergoing bariatric surgery infected with COVID-19 with and without vaccination. COVID-19 severity was assessed based on the Egypt Ministry of Health guidelines. Some patients were isolated at home, whereas others were hospitalised.
During the one year after the restart of bariatric surgery procedures, 606 patients underwent bariatric procedures (n = 280 fully vaccinated, n = 320 unvaccinated). During follow-up, that period, the incidence of COVID-19 in the vaccinated group was 1.07% (n = 3) versus 14.1% (n = 46) in the unvaccinated group.Three patients had mild symptoms in the vaccinated group, and no hospital admission was necessary. In the unvaccinated group, 27 patients (60%) were classified as mild, eight (17.8%) as moderate, eight (17.8%) as moderate with risk, and two (4.4%) as severe; the mortality rate was 0%. Of these, 16 (88.9%) were hospitalised, of which six (33.3%) were admitted to the intensive care unit in the moderate to severe groups.
Patients with obesity are at increased risk for COVID-19 infection and adverse consequences. Our findings showed a higher incidence of COVID-19 among those unvaccinated versus vaccinated. Therefore, at least during times and locations of a COVID-19 pandemic, vaccinations may be beneficial for patients against COVID-19 prior to bariatric surgery.
本研究旨在描述在埃及亚历山大的麦地那女子医院恢复减肥手术程序后的第一年里,新冠病毒检测呈阳性的全程接种疫苗和未接种疫苗患者的发病率及临床表现。(该诊所于2020年3月关闭,并于2020年10月中旬重新开放)。
这项前瞻性队列研究于2020年11月至2021年12月底进行。我们确定了接受减肥手术且感染新冠病毒的接种疫苗和未接种疫苗的患者。根据埃及卫生部指南评估新冠病毒的严重程度。一些患者在家中隔离,而其他患者住院治疗。
在减肥手术程序重启后的一年中,606例患者接受了减肥手术(n = 280例全程接种疫苗,n = 320例未接种疫苗)。在该随访期间,接种疫苗组的新冠病毒发病率为1.07%(n = 3),而未接种疫苗组为14.1%(n = 46)。接种疫苗组有3例患者出现轻微症状,无需住院。在未接种疫苗组中,27例患者(60%)被归类为轻症,8例(17.8%)为中症,8例(17.8%)为中症伴风险,2例(4.4%)为重症;死亡率为0%。其中,16例(88.9%)住院治疗,其中6例(33.3%)在中重症组被收入重症监护病房。
肥胖患者感染新冠病毒及出现不良后果的风险增加。我们的研究结果显示,未接种疫苗者的新冠病毒发病率高于接种疫苗者。因此,至少在新冠病毒大流行的时期和地点,接种疫苗可能有助于减肥手术患者预防新冠病毒。