Bragin A G
Zh Vyssh Nerv Deiat Im I P Pavlova. 1986 Sep-Oct;36(5):930-8.
The barrelfield of the adult rats was removed by suction and embryonic tissue of the somatosensory neocortex was transplanted into the cavity. Spontaneous and evoked activity of the grafted neurones was investigated extracellularly 2-3 months after the grafting. The light microscopy of the grafts revealed the presence of normal neuronal cells, but their distribution was diffuse, and they were not organized into barrels as in intact neocortex. The background activity of grafted neurones depended upon the level of the recipient's anaesthesia. The response types of the grafted neurones to vibrissae deflection and to tactile stimulation of the host body surfaces, their latencies and lability did not differ from such of the intact somatosensory cortex, but the receptive fields of the grafted neurones were larger. There was also substantial convergence of inputs from other surfaces upon the grafted neurones. The effectiveness of stimulation of the various skin areas was determined by the proximity of their neocortical representations to the graft.
通过抽吸去除成年大鼠的桶状皮质区域，并将体感新皮质的胚胎组织移植到该腔隙中。移植后2 - 3个月，在细胞外研究移植神经元的自发活动和诱发活动。移植组织的光学显微镜检查显示存在正常的神经元细胞，但其分布是弥散的，并且它们没有像在完整新皮质中那样组织成桶状。移植神经元的背景活动取决于受体的麻醉水平。移植神经元对触须偏转和宿主身体表面触觉刺激的反应类型、潜伏期和易变性与完整体感皮质的神经元没有差异，但移植神经元的感受野更大。来自其他表面的输入在移植神经元上也有大量汇聚。刺激不同皮肤区域的有效性取决于它们在新皮质中的代表区域与移植部位的接近程度。
