Zhou Xiaocong, Wang Jian, Shen Yirui, Ma Dumei, Zhao Yufen, Wu Ju
Institute of Drug Discovery Technology, Ningbo University, Zhejiang 315211, China.
School of Materials and Chemical Engineering, Ningbo University of Technology, Ningbo 315211, Zhejiang China.
J Org Chem. 2023 Dec 15;88(24):17521-17526. doi: 10.1021/acs.joc.3c02017. Epub 2023 Nov 22.
An efficient and environmentally friendly electrochemical synthesis of phosphorylated oxindoles and indolo[2,1-]isoquinolin-6(5)-ones mediated by readily available CpFe has been developed, which illustrated a broad substrate scope and diverse functional group compatibility. This protocol featured an external oxidant-free process and was at room temperature, which was proposed to be driven by the anodic oxidation of CpFe.
已开发出一种由易于获得的CpFe介导的高效且环境友好的电化学合成磷酸化氧化吲哚和吲哚并[2,1-]异喹啉-6(5)-酮的方法，该方法展示了广泛的底物范围和多样的官能团兼容性。该方案具有无外部氧化剂的过程且在室温下进行，据推测是由CpFe的阳极氧化驱动的。
