与 COVID-19 疫苗接种相关的内分泌疾病：病例报告。
Endocrine diseases associated with COVID-19 vaccination: case report.
机构信息
Servicio de Endocrinología, Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.
Servicio de Banco de Órganos y Laboratorio de Histocompatibilidad, Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.
出版信息
Rev Peru Med Exp Salud Publica. 2023 Jul-Sep;40(3):364-368. doi: 10.17843/rpmesp.2023.403.12572. Epub 2023 Sep 28.
SARS-CoV-2 vaccination is not free of adverse effects. We present two cases of endocrine involvement associated with COVID-19 vaccination. A 46-year-old woman who, after receiving the first COVID-19 vaccination dose, presented persistent fever and signs of thyrotoxicosis after being diagnosed with subacute thyroiditis associated with COVID-19 vaccination; the condition remitted with the use of corticoids. A 71-year-old male, who after COVID-19 vaccination, presented hyperinsulinemic hypoglycemia, testing positive for anti-insulin antibodies; he was diagnosed with autoimmune hypoglycemia associated with COVID-19 vaccination and received treatment with prednisone, controlling the episodes of hypoglycemia. In conclusion, endocrine diseases associated with COVID-19 vaccination are extremely rare and their timely detection allows adequate treatment.
SARS-CoV-2 疫苗接种并非没有不良反应。我们报告两例与 COVID-19 疫苗接种相关的内分泌系统受累病例。一位 46 岁女性在接种第一剂 COVID-19 疫苗后，被诊断为与 COVID-19 疫苗接种相关的亚急性甲状腺炎，出现持续发热和甲状腺毒症的迹象；在使用皮质激素后，病情缓解。一位 71 岁男性在接种 COVID-19 疫苗后，出现高胰岛素血症低血糖，胰岛素抗体检测阳性；他被诊断为与 COVID-19 疫苗接种相关的自身免疫性低血糖，并接受泼尼松治疗，控制低血糖发作。总之，与 COVID-19 疫苗接种相关的内分泌疾病极为罕见，及时发现可进行充分治疗。
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